% Bibliography for hypothesis h-827a821b
% Title: Metabolic Reprogramming via Coordinated Multi-Gene CRISPR Circuits
% Generated: 2026-04-28T21:01:29Z

@article{pmid41743852,
  title = {Targeting a Shared Mitophagy Regulator: The SIRT1-FOXO3-DEPP1 Axis Underpins the Dual Bone and Brain Benefits of Total Flavonoids from Drynaria fortunei.},
  author = {Zhang Y, Guo X, Wang Q, Xiao L, Liu Q, Gan Y, Li Y, Sun C, Luo Z, Sun K, Tao W, Wei X},
  journal = {Research (Washington, D.C.)},
  year = {2026},
  pmid = {41743852},
  doi = {10.34133/research.1125},
  url = {https://pubmed.ncbi.nlm.nih.gov/41743852/},
}

@article{pmid40108474,
  title = {VDAC2 loss elicits tumour destruction and inflammation for cancer therapy.},
  author = {Yuan S, Sun R, Shi H, Chapman NM, Hu H, Guy C, Rankin S, Kc A, Palacios G, Meng X, Sun X, Zhou P, Yang X, Gottschalk S, Chi H},
  journal = {Nature},
  year = {2025},
  pmid = {40108474},
  doi = {10.1038/s41586-025-08732-6},
  url = {https://pubmed.ncbi.nlm.nih.gov/40108474/},
}

@article{pmid37267686,
  title = {Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis.},
  author = {Zhong S, Chen W, Wang B, Gao C, Liu X, Song Y, Qi H, Liu H, Wu T, Wang R, Chen B},
  journal = {Redox biology},
  year = {2023},
  pmid = {37267686},
  doi = {10.1016/j.redox.2023.102760},
  url = {https://pubmed.ncbi.nlm.nih.gov/37267686/},
}

@article{pmid37705748,
  title = {Sirtuin-3 activates the mitochondrial unfolded protein response and reduces cerebral ischemia/reperfusion injury.},
  author = {Xiaowei X, Qian X, Dingzhou Z},
  journal = {International journal of biological sciences},
  year = {2023},
  pmid = {37705748},
  doi = {10.7150/ijbs.86614},
  url = {https://pubmed.ncbi.nlm.nih.gov/37705748/},
}

@article{pmid35173339,
  title = {Magnetic control of tokamak plasmas through deep reinforcement learning.},
  author = {Degrave J, Felici F, Buchli J, Neunert M, Tracey B, Carpanese F, Ewalds T, Hafner R, Abdolmaleki A, de Las Casas D, Donner C, Fritz L, Galperti C, Huber A, Keeling J, Tsimpoukelli M, Kay J, Merle A, Moret JM, Noury S, Pesamosca F, Pfau D, Sauter O, Sommariva C, Coda S, Duval B, Fasoli A, Kohli P, Kavukcuoglu K, Hassabis D},
  journal = {Nature},
  year = {2022},
  pmid = {35173339},
  doi = {10.1038/s41586-021-04301-9},
  url = {https://pubmed.ncbi.nlm.nih.gov/35173339/},
}

@article{pmid35221331,
  title = {Phosphorylated NFS1 weakens oxaliplatin-based chemosensitivity of colorectal cancer by preventing PANoptosis.},
  author = {Lin JF, Hu PS, Wang YY, Tan YT, Yu K, Liao K, Wu QN, Li T, Meng Q, Lin JZ, Liu ZX, Pu HY, Ju HQ, Xu RH, Qiu MZ},
  journal = {Signal transduction and targeted therapy},
  year = {2022},
  pmid = {35221331},
  doi = {10.1038/s41392-022-00889-0},
  url = {https://pubmed.ncbi.nlm.nih.gov/35221331/},
}

@article{pmid36057161,
  title = {LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization.},
  author = {Chen Y, Wu G, Li M, Hesse M, Ma Y, Chen W, Huang H, Liu Y, Xu W, Tang Y, Zheng H, Li C, Lin Z, Chen G, Liao W, Liao Y, Bin J, Chen Y},
  journal = {Redox biology},
  year = {2022},
  pmid = {36057161},
  doi = {10.1016/j.redox.2022.102446},
  url = {https://pubmed.ncbi.nlm.nih.gov/36057161/},
}

@article{pmid33199879,
  title = {Cardiomyocyte-derived calcitonin regulates atrial fibrosis and AF.},
  author = {Fernández-Ruiz I},
  journal = {Nature reviews. Cardiology},
  year = {2021},
  pmid = {33199879},
  doi = {10.1038/s41569-020-00479-z},
  url = {https://pubmed.ncbi.nlm.nih.gov/33199879/},
}

@article{pmid33446582,
  title = {Complete Genome Sequence of Geobacter sp. Strain FeAm09, a Moderately Acidophilic Soil Bacterium.},
  author = {Yadav P, Antony-Babu S, Hayes E, Healy OM, Pan D, Yang WH, Silver WL, Anderson CL, Voshall A, Fernando SC, Moriyama EN, Herr JR, Weber KA},
  journal = {Microbiology resource announcements},
  year = {2021},
  pmid = {33446582},
  doi = {10.1128/MRA.00979-20},
  url = {https://pubmed.ncbi.nlm.nih.gov/33446582/},
}

@article{pmid34469734,
  title = {SMS2 deficiency impairs PKCδ-regulated B cell tolerance in the germinal center.},
  author = {Ou P, Stanek A, Huan Z, Roman CAJ, Huan C},
  journal = {Cell reports},
  year = {2021},
  pmid = {34469734},
  doi = {10.1016/j.celrep.2021.109624},
  url = {https://pubmed.ncbi.nlm.nih.gov/34469734/},
}

@article{pmid32470790,
  title = {Multifaceted targeting of neurodegeneration with bioactive molecules of saffron (Crocus sativus): An insilco evidence-based hypothesis.},
  author = {["Krishnaswamy V", "Alugoju P", "Periyasamy L"]},
  journal = {Medical hypotheses},
  year = {2020},
  pmid = {32470790},
  doi = {10.1016/j.mehy.2020.109872},
}

@article{pmid28611284,
  title = {Activation of the ATF2/CREB-PGC-1α pathway by metformin leads to dopaminergic neuroprotection.},
  author = {["Kang H", "Khang R", "Ham S", "Jeong G", "Kim H", "Jo M", "Lee B", "Lee Y", "Jo A", "Park C"]},
  journal = {Oncotarget},
  year = {2017},
  pmid = {28611284},
  doi = {10.18632/oncotarget.18122},
}

@article{pmid25798616,
  title = {NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage.},
  author = {["Xiong W", "MacColl Garfinkel A", "Li Y", "Benowitz L", "Cepko C"]},
  journal = {The Journal of clinical investigation},
  year = {2015},
  pmid = {25798616},
  doi = {10.1172/JCI79735},
}

@article{pmid19376812,
  title = {Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia.},
  author = {["Coppola G", "Marmolino D", "Lu D", "Wang Q", "Cnop M", "Rai M", "Acquaviva F", "Cocozza S", "Pandolfo M", "Geschwind D"]},
  journal = {Human molecular genetics},
  year = {2009},
  pmid = {19376812},
  doi = {10.1093/hmg/ddp183},
}