% Bibliography for hypothesis h-7ed5dae4
% Title: TDP-43 Pathology Creates a Distinct Epigenetic Clock "Signature Divergence" Detectable in Middle Temporal Gyrus — A New Biomarker Axis for LATE vs. AD
% Generated: 2026-04-28T19:33:13Z

@article{pmid40157356,
  title = {TDP-43 seeding induces cytoplasmic aggregation heterogeneity and nuclear loss of function of TDP-43.},
  author = {["Rummens Jens", "Khalil Bilal", "Y\u0131ld\u0131r\u0131m G\u00fcnseli", "Silva Pedro", "Zorzini Valentina"]},
  journal = {Neuron},
  year = {2025},
  pmid = {40157356},
  doi = {10.1016/j.neuron.2025.03.004},
}

@article{pmid40157356,
  title = {TDP-43 seeding induces cytoplasmic aggregation heterogeneity and nuclear loss of function of TDP-43.},
  author = {Rummens Jens; Khalil Bilal; Yıldırım Günseli; Silva Pedro; Zorzini Valentina; Peredo Nicolas; Wojno Marta; Ramakers Meine; Van Den Bosch Ludo; Van Damme Philip; Davie Kristofer; Hendrix Jelle; Rousseau Frederic; Schymkowitz Joost; Da Cruz Sandrine},
  journal = {Neuron},
  year = {2025},
  pmid = {40157356},
  doi = {10.1016/j.neuron.2025.03.004},
}

@article{pmid38079474,
  title = {The new missense G376V-TDP-43 variant induces late-onset distal myopathy but not amyotrophic lateral sclerosis.},
  journal = {Brain : a journal of neurology},
  year = {2024},
  pmid = {38079474},
  doi = {10.1093/brain/awad410},
}

@article{pmid38079474,
  title = {The new missense G376V-TDP-43 variant induces late-onset distal myopathy but not amyotrophic lateral sclerosis.},
  author = {Zibold, Lessard, Picard, da Silva, Zadorozhna et al.},
  journal = {Brain : a journal of neurology},
  year = {2024},
  pmid = {38079474},
}

@article{pmid39327159,
  title = {TDP-43 nuclear condensation and neurodegenerative proteinopathies.},
  journal = {Trends in neurosciences},
  year = {2024},
  pmid = {39327159},
  doi = {10.1016/j.tins.2024.09.003},
}

@article{pmid39327159,
  title = {TDP-43 nuclear condensation and neurodegenerative proteinopathies.},
  author = {Vassallu, Igaz},
  journal = {Trends in neurosciences},
  year = {2024},
  pmid = {39327159},
}

@article{pmid35112738,
  title = {Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.},
  author = {Gruijs da Silva LA, Simonetti F, Hutten S, Riemenschneider H, Sternburg EL, Pietrek LM, Gebel J, Dötsch V, Edbauer D, Hummer G, Stelzl LS, Dormann D},
  journal = {The EMBO journal},
  year = {2022},
  pmid = {35112738},
  doi = {10.15252/embj.2021108443},
  url = {https://pubmed.ncbi.nlm.nih.gov/35112738/},
}

@article{pmid35112738,
  title = {Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.},
  author = {Gruijs da Silva LA, Simonetti F, Hutten S, Riemenschneider H, Sternburg EL, Pietrek LM, Gebel J, Dötsch V, Edbauer D, Hummer G, Stelzl LS, Dormann D},
  journal = {The EMBO journal},
  year = {2022},
  pmid = {35112738},
}

@article{pmid33446423,
  title = {FUS and TDP-43 Phases in Health and Disease.},
  author = {["Portz Bede", "Lee Bo Lim", "Shorter James"]},
  journal = {Trends in biochemical sciences},
  year = {2021},
  pmid = {33446423},
  doi = {10.1101/2020.08.28.272377},
}

@article{pmid33446423,
  title = {FUS and TDP-43 Phases in Health and Disease.},
  author = {["Portz Bede", "Lee Bo Lim", "Shorter James"]},
  journal = {Trends in biochemical sciences},
  year = {2021},
  pmid = {33446423},
}