% Bibliography for hypothesis h-7a8d7379
% Title: Piezoelectric Nanochannel BBB Disruption
% Generated: 2026-04-28T13:58:38Z

@article{pmid40994007,
  title = {Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.},
  author = {["Cueva Vargas J", "Belforte N", "Vidal-Paredes I", "Dotigny F", "Vande Velde C", "Quintero H", "Di Polo A"]},
  journal = {Molecular therapy : the journal of the American Society of Gene Therapy},
  year = {2026},
  pmid = {40994007},
  doi = {10.1016/j.ymthe.2025.09.037},
}

@article{pmid41197818,
  title = {ROS-responsive nanogels for brain targeted delivery of icariin in the treatment of Parkinson's disease.},
  author = {["Li X", "Huang J", "Zhou Y", "Chen X", "Dong Q", "Cui Y", "Chen Y"]},
  journal = {International journal of pharmaceutics},
  year = {2026},
  pmid = {41197818},
  doi = {10.1016/j.ijpharm.2025.126361},
}

@article{pmid41399659,
  title = {Claudins proteins in brain tumors: expression patterns and therapeutic target.},
  author = {["Romanowicz A", "\u0141ukaszewicz-Zaj\u0105c M", "Mroczko B"]},
  journal = {Biochemia medica},
  year = {2026},
  pmid = {41399659},
  doi = {10.11613/BM.2026.010501},
}

@article{pmid41594443,
  title = {Testicular Gap (CX43) and Tight Junction (OCLN, CLDN3, 5 and 11) Components in the Dog Are Affected by GnRH-Mediated Downregulation.},
  author = {Goericke-Pesch S, Röhrs L, Wallrabenstein S, Frimødt Rønnow A, Fietz D, Brehm R, Langeheine M, Wehrend A, Hoffmann B, Körber H, Packeiser EM},
  journal = {Animals : an open access journal from MDPI},
  year = {2026},
  pmid = {41594443},
  doi = {10.3390/ani16020254},
  url = {https://pubmed.ncbi.nlm.nih.gov/41594443/},
}

@article{pmid39975311,
  title = {Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.},
  author = {["Cueva-Vargas J", "Belforte N", "Vidal-Paredes I", "Dotigny F", "Vande Velde C", "Quintero H", "Di Polo A"]},
  journal = {bioRxiv : the preprint server for biology},
  year = {2025},
  pmid = {39975311},
  doi = {10.1101/2024.12.21.629919},
}

@article{pmid39985305,
  title = {Dolutegravir induces endoplasmic reticulum stress at the blood-brain barrier.},
  author = {Huang C, Qu QR, Hoque MT, Bendayan R},
  journal = {FASEB J},
  year = {2025},
  pmid = {39985305},
  doi = {10.1096/fj.202402677RR},
  url = {https://pubmed.ncbi.nlm.nih.gov/39985305},
}

@article{pmid40018968,
  title = {Claudin-1 impairs blood-brain barrier by downregulating endothelial junctional proteins in traumatic brain injury.},
  author = {Gowrikumar S, Tarudji A, McDonald BZ, Balusa SS, Kievit FM, Dhawan P},
  journal = {Tissue barriers},
  year = {2025},
  pmid = {40018968},
  doi = {10.1080/21688370.2025.2470482},
  url = {https://pubmed.ncbi.nlm.nih.gov/40018968/},
}

@article{pmid40244194,
  title = {Mesenchymal Stem Cells Restore Endothelial Integrity and Alleviate Emotional Impairments in a Diabetic Mouse Model via Inhibition of MMP-9 Activity.},
  author = {["Chen A", "Duan Y", "Zhou S", "Du F", "Peng H", "Zeng D", "Wang J", "Wu Y", "Shi S", "Li S"]},
  journal = {International journal of molecular sciences},
  year = {2025},
  pmid = {40244194},
  doi = {10.3390/ijms26073355},
}

@article{pmid40429705,
  title = {Profiling Tight Junction Protein Expression in Brain Vascular Malformations.},
  author = {Pedrosa L, Mosteiro A, Reyes L, Amaro S, Menéndez-Girón S, Rivera MC, Domínguez CJ, Planas AM, Torné R, Rodríguez-Hernández A},
  journal = {Int J Mol Sci},
  year = {2025},
  pmid = {40429705},
  doi = {10.3390/ijms26104558},
  url = {https://pubmed.ncbi.nlm.nih.gov/40429705},
}

@article{pmid40493345,
  title = {Artemether Improves Aβ},
  author = {["Cai J", "Liu Y", "Gong L", "Deng S", "Zheng W", "Li S"]},
  journal = {Molecular neurobiology},
  year = {2025},
  pmid = {40493345},
  doi = {10.1007/s12035-025-05141-8},
}

@article{pmid40533746,
  title = {Exosomes as nanocarriers for brain-targeted delivery of therapeutic nucleic acids: advances and challenges.},
  author = {["Sanadgol N", "Abedi M", "Hashemzaei M", "Kamran Z", "Khalseh R", "Beyer C", "Voelz C"]},
  journal = {Journal of nanobiotechnology},
  year = {2025},
  pmid = {40533746},
  doi = {10.1186/s12951-025-03528-2},
}

@article{pmid41199078,
  title = {Bionanoconjugates in Neurodegeneration: Peptide-Nanoparticle Alliances for Next-Generation Therapies.},
  author = {["Ranjitha V", "Kumar A", "Kaalappa P"]},
  journal = {Pharmaceutical research},
  year = {2025},
  pmid = {41199078},
  doi = {10.1007/s11095-025-03941-0},
}

@article{pmid36969875,
  title = {Antiretroviral drugs efavirenz, dolutegravir and bictegravir dysregulate blood-brain barrier integrity and function.},
  author = {["Huang C", "Hoque T", "Bendayan R"]},
  journal = {Frontiers in pharmacology},
  year = {2023},
  pmid = {36969875},
  doi = {10.3389/fphar.2023.1118580},
}

@article{pmid33280500,
  title = {Autophagy alleviates hypoxia-induced blood-brain barrier injury via regulation of CLDN5 (claudin 5).},
  author = {Yang Z, Lin P, Chen B, Zhang X, Xiao W, Wu S, Huang C, Feng D, Zhang W, Zhang J},
  journal = {Autophagy},
  year = {2021},
  pmid = {33280500},
  doi = {10.1080/15548627.2020.1851897},
  url = {https://pubmed.ncbi.nlm.nih.gov/33280500},
}

@article{pmid28490769,
  title = {Increased cerebral expressions of MMPs, CLDN5, OCLN, ZO1 and AQPs are associated with brain edema following fatal heat stroke.},
  author = {Du Y, Xu JT, Jin HN, Zhao R, Zhao D, Du SH, Xue Y, Xie XL, Wang Q},
  journal = {Scientific reports},
  year = {2017},
  pmid = {28490769},
  doi = {10.1038/s41598-017-01923-w},
  url = {https://pubmed.ncbi.nlm.nih.gov/28490769/},
}

@article{pmid27660013,
  title = {Anti-inflammatory activity of Barleria lupulina: Identification of active compounds that activate the Nrf2 cell defense pathway, organize cortical actin, reduce stress fibers, and improve cell junctions in microvascular endothelial cells.},
  author = {["Senger D", "Hoang M", "Kim K", "Li C", "Cao S"]},
  journal = {Journal of ethnopharmacology},
  year = {2016},
  pmid = {27660013},
  doi = {10.1016/j.jep.2016.09.017},
}