% Bibliography for hypothesis h-69919c49
% Title: PARP1 Inhibition Therapy
% Generated: 2026-04-28T15:36:20Z

@article{pmid41499130,
  title = {Defective DNA Damage Response Is a Targetable Therapeutic Vulnerability in ESR1-Mutant Breast Cancer.},
  author = {Herzog SK, Stevens JH, Gu G, Grimm SL, Cardoza K et al.},
  journal = {Cancer Res},
  year = {2026},
  pmid = {41499130},
  doi = {doi: 10.1158/0008-5472.CAN-24-3891},
  url = {https://pubmed.ncbi.nlm.nih.gov/41499130/},
}

@article{pmid41864203,
  title = {Replicative gaps in DNA damage tolerance, genome instability, and cancer therapy.},
  author = {Falbo L, Costanzo V},
  journal = {Mol Cell},
  year = {2026},
  pmid = {41864203},
  doi = {doi: 10.1016/j.molcel.2026.02.018},
  url = {https://pubmed.ncbi.nlm.nih.gov/41864203/},
}

@article{pmid41922367,
  title = {Versatile and sensitive detection of mono- and poly(ADP-ribosyl)ation reveals XRCC1-dependent remodelling of PARP1 signalling.},
  author = {Dauben H, Mihaljević M, Kolvenbach A, Palumbieri MD, Kapsali C et al.},
  journal = {Nat Commun},
  year = {2026},
  pmid = {41922367},
  doi = {doi: 10.1038/s41467-026-71311-4},
  url = {https://pubmed.ncbi.nlm.nih.gov/41922367/},
}

@article{pmid41931203,
  title = {Differential proteomic responses to short-term heat stress in Vechur and crossbred cattle of Kerala.},
  author = {Anisha J P; Shynu M; Radhika G; Beena V; Uma R; Lijo J; Asaf V N Muhasin; Gleeja V L},
  journal = {Tropical animal health and production},
  year = {2026},
  pmid = {41931203},
  doi = {10.1007/s11250-026-05018-5},
  url = {https://pubmed.ncbi.nlm.nih.gov/41931203/},
}

@article{pmid41931484,
  title = {Differential sensitivity of MCPH1- and BRCA2-deficient cancer cells to PARP-1 inhibition.},
  author = {Chapman IG, Wu X, Veuger S, Jowsey PA},
  journal = {PLoS One},
  year = {2026},
  pmid = {41931484},
  doi = {doi: 10.1371/journal.pone.0345514},
  url = {https://pubmed.ncbi.nlm.nih.gov/41931484/},
}

@article{pmid40442774,
  title = {Clinical approaches to overcome PARP inhibitor resistance.},
  author = {["Zou Y", "Zhang H", "Chen P", "Tang J", "Yang S", "Nicot C", "Guan Z", "Li X", "Tang H"]},
  journal = {Molecular cancer},
  year = {2025},
  pmid = {40442774},
  doi = {10.1186/s12943-025-02355-1},
}

@article{pmid40905723,
  title = {Tipping the PARylation scale: Dysregulation of PAR signaling in Huntington and neurodegenerative diseases.},
  author = {Peng C, Maiuri T, Truant R},
  journal = {Journal of Huntington's disease},
  year = {2025},
  pmid = {40905723},
  doi = {10.1177/18796397251372667},
  url = {https://pubmed.ncbi.nlm.nih.gov/40905723/},
}

@article{pmid40913912,
  title = {Targeting KCNN4 channels modulates microglial activation and apoptosis in a PD-relevant inflammatory model.},
  author = {["Hung H", "Li I", "Lin Y", "Yeh T", "Ng K", "Wang T", "Hong K", "Wang T", "Wu Y", "Shih J"]},
  journal = {Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year = {2025},
  pmid = {40913912},
  doi = {10.1016/j.biopha.2025.118526},
}

@article{pmid41022359,
  title = {Roles and therapeutic potential of PARP-1 in neurodegenerative diseases.},
  author = {["Liu C", "Lai F", "Zhang T", "Mao K", "Wan H", "He Y"]},
  journal = {Biochemical pharmacology},
  year = {2025},
  pmid = {41022359},
  doi = {10.1016/j.bcp.2025.117373},
}

@article{pmid41102145,
  title = {Increased nucleotide metabolism alleviates Alzheimer's disease pathology.},
  author = {["Yu Y", "Miller M", "Huang A", "Tan B", "Celardo I", "Leal N", "Loh S", "Martins L"]},
  journal = {Cell death & disease},
  year = {2025},
  pmid = {41102145},
  doi = {10.1038/s41419-025-08066-1},
}

@article{pmid41178110,
  title = {Targeting Poly (ADP-Ribose) Polymerase-1 for the Treatment of Neurodegenerative Diseases.},
  author = {Polk S, Rassaeikashuk M, Thilagavathi R, Selvam C},
  journal = {Chemical biology & drug design},
  year = {2025},
  pmid = {41178110},
  doi = {10.1111/cbdd.70189},
  url = {https://pubmed.ncbi.nlm.nih.gov/41178110/},
}

@article{pmid41460301,
  title = {PARPs and PARP inhibitors: molecular mechanisms and clinical applications.},
  author = {Wang F, Guo Z, Carr MJ, Shi W},
  journal = {Molecular biomedicine},
  year = {2025},
  pmid = {41460301},
  doi = {10.1186/s43556-025-00385-1},
  url = {https://pubmed.ncbi.nlm.nih.gov/41460301/},
}

@article{pmid38396375,
  title = {Blocking the Self-Destruct Program of Dopamine Neurons through Macrophage Migration Inhibitory Factor Nuclease Inhibition.},
  author = {["Patel J", "Dawson V", "Dawson T"]},
  journal = {Movement disorders : official journal of the Movement Disorder Society},
  year = {2024},
  pmid = {38396375},
  doi = {10.1002/mds.29748},
}

@article{pmid38509368,
  title = {Transcription-replication conflicts underlie sensitivity to PARP inhibitors.},
  author = {Petropoulos M, Karamichali A, Rossetti GG, Freudenmann A, Iacovino LG, Dionellis VS, Sotiriou SK, Halazonetis TD},
  journal = {Nature},
  year = {2024},
  pmid = {38509368},
  doi = {10.1038/s41586-024-07217-2},
  url = {https://pubmed.ncbi.nlm.nih.gov/38509368},
}

@article{pmid38512229,
  title = {PARP Inhibitors for Breast Cancer Treatment: A Review.},
  author = {["Morganti S", "Marra A", "De Angelis C", "Toss A", "Licata L", "Giugliano F", "Taurelli Salimbeni B", "Berton Giachetti P", "Esposito A", "Giordano A"]},
  journal = {JAMA oncology},
  year = {2024},
  pmid = {38512229},
  doi = {10.1001/jamaoncol.2023.7322},
}

@article{pmid38750651,
  title = {PARP1 in the intersection of different DNA repair pathways, memory formation, and sleep pressure in neurons.},
  author = {["Feltes B", "Alvares L"]},
  journal = {Journal of neurochemistry},
  year = {2024},
  pmid = {38750651},
  doi = {10.1111/jnc.16131},
}

@article{pmid38778348,
  title = {PARP1-DOT1L transcription axis drives acquired resistance to PARP inhibitor in ovarian cancer.},
  author = {Liu C, Li J, Xu F, Chen L, Ni M, Wu J, Zhao H, Wu Y, Li J, Wu X},
  journal = {Mol Cancer},
  year = {2024},
  pmid = {38778348},
  doi = {10.1186/s12943-024-02025-8},
  url = {https://pubmed.ncbi.nlm.nih.gov/38778348},
}

@article{pmid39326690,
  title = {A comprehensive review of PRAME and BAP1 in melanoma: Genomic instability and immunotherapy targets.},
  author = {["Aljabali A", "Tambuwala M", "El-Tanani M", "Hassan S", "Lundstrom K", "Mishra V", "Mishra Y", "Hromi\u0107-Jahjefendi\u0107 A", "Redwan E", "Uversky V"]},
  journal = {Cellular signalling},
  year = {2024},
  pmid = {39326690},
  doi = {10.1016/j.cellsig.2024.111434},
}

@article{pmid39480453,
  title = {Efficacy of Adding Veliparib to Temozolomide for Patients With MGMT-Methylated Glioblastoma: A Randomized Clinical Trial.},
  author = {["Sarkaria J", "Ballman K", "Kizilbash S", "Sulman E", "Giannini C", "Friday B", "Butowski N", "Mohile N", "Piccioni D", "Battiste J"]},
  journal = {JAMA oncology},
  year = {2024},
  pmid = {39480453},
  doi = {10.1001/jamaoncol.2024.4361},
}

@article{pmid39536107,
  title = {USP1 deubiquitinates PARP1 to regulate its trapping and PARylation activity.},
  author = {Nespolo A, Stefenatti L, Pellarin I, Gambelli A, Rampioni Vinciguerra GL, Karimbayli J, Barozzi S, Orsenigo F, Spizzo R, Nicoloso MS},
  journal = {Sci Adv},
  year = {2024},
  pmid = {39536107},
  doi = {10.1126/sciadv.adp6567},
  url = {https://pubmed.ncbi.nlm.nih.gov/39536107},
}

@article{pmid36220889,
  title = {C9orf72 functions in the nucleus to regulate DNA damage repair.},
  author = {["He L", "Liang J", "Chen C", "Chen J", "Shen Y", "Sun S", "Li L"]},
  journal = {Cell death and differentiation},
  year = {2023},
  pmid = {36220889},
  doi = {10.1038/s41418-022-01074-0},
}

@article{pmid37683629,
  title = {NAD(+) rescues aging-induced blood-brain barrier damage via the CX43-PARP1 axis.},
  author = {Zhan R, Meng X, Tian D, Xu J, Cui H, Yang J, Xu Y, Shi M, Xue J, Yu W},
  journal = {Neuron},
  year = {2023},
  pmid = {37683629},
  doi = {10.1016/j.neuron.2023.08.010},
  url = {https://pubmed.ncbi.nlm.nih.gov/37683629},
}

@article{pmid34139099,
  title = {Metastasis of pulmonary adenocarcinoma to the thyroid closely mimics papillary thyroid carcinoma.},
  author = {Ching-Ling Tu; Chih-Hung Lin},
  journal = {The Kaohsiung journal of medical sciences},
  year = {2022},
  pmid = {34139099},
  doi = {10.1002/kjm2.12410},
}

@article{pmid35273392,
  title = {Museum of spatial transcriptomics.},
  author = {["Moses L", "Pachter L"]},
  journal = {Nature methods},
  year = {2022},
  pmid = {35273392},
  doi = {10.1038/s41592-022-01409-2},
}

@article{pmid35567890,
  title = {Characterisation of chemical, microbial and sensory profiles of commercial kombuchas.},
  author = {["Andreson M", "Kazantseva J", "Kuldj\u00e4rv R", "Malv E", "Vaikma H", "Kaleda A", "K\u00fctt M", "Vilu R"]},
  journal = {International journal of food microbiology},
  year = {2022},
  pmid = {35567890},
  doi = {10.1016/j.ijfoodmicro.2022.109715},
}

@article{pmid35732740,
  title = {Life rather than climate influences diversity at scales greater than 40 million years.},
  author = {["Spiridonov A", "Lovejoy S"]},
  journal = {Nature},
  year = {2022},
  pmid = {35732740},
  doi = {10.1038/s41586-022-04867-y},
}

@article{pmid36569329,
  title = {Natural phytochemicals prevent side effects in },
  author = {["Wang C", "Gao P", "Xu J", "Liu S", "Tian W", "Liu J", "Zhou L"]},
  journal = {Frontiers in pharmacology},
  year = {2022},
  pmid = {36569329},
  doi = {10.3389/fphar.2022.1078303},
}

@article{pmid33387580,
  title = {Poly (ADP-ribose) polymerase-1 as a promising drug target for neurodegenerative diseases.},
  author = {["Thapa K", "Khan H", "Sharma U", "Grewal A", "Singh T"]},
  journal = {Life sciences},
  year = {2021},
  pmid = {33387580},
  doi = {10.1016/j.lfs.2020.118975},
}

@article{pmid33657415,
  title = {Avoid the trap: Targeting PARP1 beyond human malignancy.},
  author = {["Kim C", "Chen C", "Yu Y"]},
  journal = {Cell chemical biology},
  year = {2021},
  pmid = {33657415},
  doi = {10.1016/j.chembiol.2021.02.004},
}

@article{pmid34234567,
  title = {Development and External Validation of Safe Discharge Criteria After Radical Gastrectomy.},
  author = {["Yu D", "Wu X", "Li X", "Liu X", "Jiang K", "Zhao Q", "Nie H"]},
  journal = {Cancer management and research},
  year = {2021},
  pmid = {34234567},
  doi = {10.2147/CMAR.S305046},
}

@article{pmid31548007,
  title = {A research agenda for bariatric surgery.},
  author = {Guilherme S Mazzini; Guilherme M Campos},
  journal = {Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery},
  year = {2020},
  pmid = {31548007},
  doi = {10.1016/j.soard.2019.07.025},
}

@article{pmid32051440,
  title = {Tension-type headache in the Emergency Department Diagnosis and misdiagnosis: The TEDDi study.},
  author = {["Garc\u00eda-Azor\u00edn D", "Farid-Zahran M", "Guti\u00e9rrez-S\u00e1nchez M", "Gonz\u00e1lez-Garc\u00eda M", "Guerrero A", "Porta-Etessam J"]},
  journal = {Scientific reports},
  year = {2020},
  pmid = {32051440},
  doi = {10.1038/s41598-020-59171-4},
}

@article{pmid32563252,
  title = {PARP inhibitor resistance: the underlying mechanisms and clinical implications.},
  author = {["Li H", "Liu Z", "Wu N", "Chen Y", "Cheng Q", "Wang J"]},
  journal = {Molecular cancer},
  year = {2020},
  pmid = {32563252},
  doi = {10.1186/s12943-020-01227-0},
}

@article{pmid32903806,
  title = {Nicotinamide, a Poly [ADP-Ribose] Polymerase 1 (PARP-1) Inhibitor, as an Adjunctive Therapy for the Treatment of Alzheimer's Disease.},
  author = {["Salech F", "Ponce D", "Paula-Lima A", "SanMartin C", "Behrens M"]},
  journal = {Frontiers in aging neuroscience},
  year = {2020},
  pmid = {32903806},
  doi = {10.3389/fnagi.2020.00255},
}

@article{pmid33059700,
  title = {Glycine, the smallest amino acid, confers neuroprotection against D-galactose-induced neurodegeneration and memory impairment by regulating c-Jun N-terminal kinase in the mouse brain.},
  author = {["Ullah R", "Jo M", "Riaz M", "Alam S", "Saeed K", "Ali W", "Rehman I", "Ikram M", "Kim M"]},
  journal = {Journal of neuroinflammation},
  year = {2020},
  pmid = {33059700},
  doi = {10.1186/s12974-020-01989-w},
}

@article{pmid31074636,
  title = {Veliparib: a new therapeutic option in ovarian cancer?},
  author = {["Ghisoni E", "Giannone G", "Tuninetti V", "Genta S", "Scotto G", "Aglietta M", "Sangiolo D", "Mittica G", "Valabrega G"]},
  journal = {Future oncology (London, England)},
  year = {2019},
  pmid = {31074636},
  doi = {10.2217/fon-2018-0883},
}

@article{pmid31395736,
  title = {MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers.},
  author = {["Srinivasan G", "Williamson E", "Kong K", "Jaiswal A", "Huang G", "Kim H", "Sch\u00e4rer O", "Zhao W", "Burma S", "Sung P"]},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year = {2019},
  pmid = {31395736},
  doi = {10.1073/pnas.1903150116},
}

@article{pmid31611390,
  title = {Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes.},
  author = {["L\u00e1zaro S", "P\u00e9rez-Crespo M", "Lorz C", "Bernardini A", "Oteo M", "Enguita A", "Romero E", "Hern\u00e1ndez P", "Tom\u00e1s L", "Morcillo M"]},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year = {2019},
  pmid = {31611390},
  doi = {10.1073/pnas.1821745116},
}

@article{pmid30177437,
  title = {Mechanisms of PARP inhibitor sensitivity and resistance.},
  author = {["D'Andrea A"]},
  journal = {DNA repair},
  year = {2018},
  pmid = {30177437},
  doi = {10.1016/j.dnarep.2018.08.021},
}

@article{pmid30356214,
  title = {Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.},
  author = {Liu H, Zhang H, Wu X, Ma D, Wu J, Wang L, Jiang Y, Fei Y, Zhu C, Tan R},
  journal = {Nature},
  year = {2018},
  pmid = {30356214},
  doi = {10.1038/s41586-018-0629-6},
  url = {https://pubmed.ncbi.nlm.nih.gov/30356214},
}

@article{pmid23143307,
  title = {8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair.},
  author = {["Sheng Z", "Oka S", "Tsuchimoto D", "Abolhassani N", "Nomaru H", "Sakumi K", "Yamada H", "Nakabeppu Y"]},
  journal = {The Journal of clinical investigation},
  year = {2012},
  pmid = {23143307},
  doi = {10.1172/JCI65053},
}

@article{pmid20181594,
  title = {NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death.},
  author = {["Alano C", "Garnier P", "Ying W", "Higashi Y", "Kauppinen T", "Swanson R"]},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year = {2010},
  pmid = {20181594},
  doi = {10.1523/JNEUROSCI.5552-09.2010},
}

@article{pmid11295153,
  title = {Niacin, poly(ADP-ribose) polymerase-1 and genomic stability.},
  author = {["Hageman G", "Stierum R"]},
  journal = {Mutation research},
  year = {2001},
  pmid = {11295153},
  doi = {10.1016/s0027-5107(01)00078-1},
}