% Bibliography for hypothesis h-41bc2d38
% Title: Adenosine-Astrocyte Metabolic Reset
% Generated: 2026-04-28T20:27:29Z

@article{pmid41756441,
  title = {De novo purine synthesis reprograms the macrophage inflammatory response and the immune response in sepsis.},
  author = {Haskó G, Liu L, Németh ZH, Wagener G, Akcan U, Arif M, Pacher P, Kelestemur T},
  journal = {Research square},
  year = {2026},
  pmid = {41756441},
  doi = {10.21203/rs.3.rs-8887742/v1},
  url = {https://pubmed.ncbi.nlm.nih.gov/41756441/},
}

@article{pmid41795299,
  title = {Parthenolide inhibits methamphetamine-induced depressive-like behavior by targeting ADORA2A.},
  author = {Hui R, Feng T, Hou C, Xu J, Zhang R, Ji M, Zhou M, Xie B, Ma S, Cong B, Ma C, Shen H, Wen D},
  journal = {Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year = {2026},
  pmid = {41795299},
  doi = {10.1016/j.phymed.2026.158030},
  url = {https://pubmed.ncbi.nlm.nih.gov/41795299/},
}

@article{pmid40986641,
  title = {Adenosine 2A receptor-dependent activation of AMPK represses TH17 cell pathogenicity through epigenetic and metabolic reprogramming.},
  author = {Papadopoulou G, Valakos D, Polydouri I, Moulara A, Vatsellas G, Angiari S, Runtsch MC, Foretz M, Viollet B, Cassotta A, O'Neill LAJ, Xanthou G},
  journal = {Science signaling},
  year = {2025},
  pmid = {40986641},
  doi = {10.1126/scisignal.adr3177},
  url = {https://pubmed.ncbi.nlm.nih.gov/40986641/},
}

@article{pmid41067595,
  title = {Endothelial adenosine receptor 2A loss alleviates diabetic vascular calcification by blocking CREB1-SNAI1-driven EndMT.},
  author = {Zhou Y, Zhao D, Ma Q, Xu J, Cai Y, Yang Q, Da Q, Sheridan K, Zhang C, Miller CL, Malhotra R, Xu S, Hong M, Huo Y},
  journal = {Pharmacological research},
  year = {2025},
  pmid = {41067595},
  doi = {10.1016/j.phrs.2025.107981},
  url = {https://pubmed.ncbi.nlm.nih.gov/41067595/},
}

@article{pmid41073355,
  title = {Surface d-Band Modulation via Biodirected Mineralization Enables Nanoenzymes to Inhibit Radiation-Induced T-Cell Exhaustion and Potentiate Immunoradiotherapy.},
  author = {Li X, Zhao Q, Feng X, Cui P, Yu J, Liang B, Liu C, Wang Y, Wu Y, Wang R, Hu B, Lin Y, Zhu L, Zhu X, Luo B, Yang X, Hu J},
  journal = {ACS nano},
  year = {2025},
  pmid = {41073355},
  doi = {10.1021/acsnano.5c09444},
  url = {https://pubmed.ncbi.nlm.nih.gov/41073355/},
}

@article{pmid41201506,
  title = {Targeting adenosine 2A receptor signaling suppresses vascular calcification by restraining smooth muscle osteogenic differentiation.},
  author = {Zhou Y, Zhao D, Ma Q, Lee S, Roh K, Cai Y, Xu J, Yang Q, Da Q, Liu Z, Ouyang K, Chantemele EJB, Hong M, Miller CL, Malhotra R, Zhang C, Xu S, Huo Y},
  journal = {Pharmacological research},
  year = {2025},
  pmid = {41201506},
  doi = {10.1016/j.phrs.2025.108012},
  url = {https://pubmed.ncbi.nlm.nih.gov/41201506/},
}

@article{pmid37291128,
  title = {Transcriptional control of pancreatic cancer immunosuppression by metabolic enzyme CD73 in a tumor-autonomous and -autocrine manner.},
  author = {Tang T, Huang X, Lu M, Zhang G, Han X, Liang T},
  journal = {Nature communications},
  year = {2023},
  pmid = {37291128},
  doi = {10.1038/s41467-023-38578-3},
  url = {https://pubmed.ncbi.nlm.nih.gov/37291128/},
}

@article{pmid33845122,
  title = {Intestinal microbiota: A potential target for enhancing the antitumor efficacy and reducing the toxicity of immune checkpoint inhibitors.},
  author = {["Luo B", "Zhang Y", "Zhang C", "Liu X", "Shi C"]},
  journal = {Cancer letters},
  year = {2021},
  pmid = {33845122},
  doi = {10.1016/j.canlet.2021.04.001},
}

@article{pmid34473957,
  title = {Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity.},
  author = {Nascimento DC, Viacava PR, Ferreira RG, Damaceno MA, Piñeros AR, Melo PH, Donate PB, Toller-Kawahisa JE, Zoppi D, Veras FP, Peres RS, Menezes-Silva L, Caetité D, Oliveira AER, Castro ÍMS, Kauffenstein G, Nakaya HI, Borges MC, Zamboni DS, Fonseca DM, Paschoal JAR, Cunha TM, Quesniaux V, Linden J, Cunha FQ, Ryffel B, Alves-Filho JC},
  journal = {Immunity},
  year = {2021},
  pmid = {34473957},
  doi = {10.1016/j.immuni.2021.08.005},
  url = {https://pubmed.ncbi.nlm.nih.gov/34473957/},
}

@article{pmid30605479,
  title = {The integration of pharmacophore-based 3D QSAR modeling and virtual screening in safety profiling: A case study to identify antagonistic activities against adenosine receptor, A2A, using 1,897 known drugs.},
  author = {["Fan F", "Toledo Warshaviak D", "Hamadeh H", "Dunn R"]},
  journal = {PloS one},
  year = {2019},
  pmid = {30605479},
  doi = {10.1371/journal.pone.0204378},
}

@article{pmid30679341,
  title = {Metabolic asymmetry and the global diversity of marine predators.},
  author = {Grady JM, Maitner BS, Winter AS, Kaschner K, Tittensor DP, Record S, Smith FA, Wilson AM, Dell AI, Zarnetske PL},
  journal = {Science},
  year = {2019},
  pmid = {30679341},
  doi = {10.1126/science.aat4220},
  url = {https://pubmed.ncbi.nlm.nih.gov/30679341},
}

@article{pmid31488706,
  title = {A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution.},
  author = {Packer JS, Zhu Q, Huynh C, Sivaramakrishnan P, Preston E, Dueck H, Stefanik D, Tan K, Trapnell C, Kim J},
  journal = {Science},
  year = {2019},
  pmid = {31488706},
  doi = {10.1126/science.aax1971},
  url = {https://pubmed.ncbi.nlm.nih.gov/31488706},
}

@article{pmid26644204,
  title = {Pharmacogenetics and induction/consolidation therapy toxicities in acute lymphoblastic leukemia patients treated with AIEOP-BFM ALL 2000 protocol.},
  author = {["Franca R", "Rebora P", "Bertorello N", "Fagioli F", "Conter V", "Biondi A", "Colombini A", "Micalizzi C", "Zecca M", "Parasole R"]},
  journal = {The pharmacogenomics journal},
  year = {2017},
  pmid = {26644204},
  doi = {10.1038/tpj.2015.83},
}

@article{pmid28224793,
  title = {A Never-Ending Story of Per- and Polyfluoroalkyl Substances (PFASs)?},
  author = {Wang Z, DeWitt JC, Higgins CP, Cousins IT},
  journal = {Environ Sci Technol},
  year = {2017},
  pmid = {28224793},
  doi = {10.1021/acs.est.6b04806},
  url = {https://pubmed.ncbi.nlm.nih.gov/28224793},
}

@article{pmid25812627,
  title = {Cord blood gene expression supports that prenatal exposure to perfluoroalkyl substances causes depressed immune functionality in early childhood.},
  author = {["Pennings J", "Jennen D", "Nygaard U", "Namork E", "Haug L", "van Loveren H", "Granum B"]},
  journal = {Journal of immunotoxicology},
  year = {2016},
  pmid = {25812627},
  doi = {10.3109/1547691X.2015.1029147},
}

@article{pmid25904789,
  title = {Gene Expression by Mouse Inner Ear Hair Cells during Development.},
  author = {Scheffer DI, Shen J, Corey DP, Chen ZY},
  journal = {J Neurosci},
  year = {2015},
  pmid = {25904789},
  doi = {10.1523/JNEUROSCI.5126-14.2015},
  url = {https://pubmed.ncbi.nlm.nih.gov/25904789},
}

@article{pmid23300412,
  title = {Chapter 6: Structural variation and medical genomics.},
  author = {Raphael BJ},
  journal = {PLoS Comput Biol},
  year = {2012},
  pmid = {23300412},
  doi = {10.1371/journal.pcbi.1002821},
  url = {https://pubmed.ncbi.nlm.nih.gov/23300412},
}

@article{pmid20164566,
  title = {Caffeine and adenosine.},
  author = {Ribeiro JA, Sebastião AM},
  journal = {J Alzheimers Dis},
  year = {2010},
  pmid = {20164566},
  doi = {10.3233/JAD-2010-1379},
  url = {https://pubmed.ncbi.nlm.nih.gov/20164566},
}

@article{pmid9160173,
  title = {Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences.},
  author = {["Lennern\u00e4s H", "Fager G"]},
  journal = {Clinical pharmacokinetics},
  year = {1997},
  pmid = {9160173},
  doi = {10.2165/00003088-199732050-00005},
}