% Bibliography for hypothesis h-3d993b5d
% Title: Metabolic Circuit Breaker via Lipid Droplet Modulation
% Generated: 2026-04-28T15:36:27Z

@article{pmid41376284,
  title = {Cerebral FURIN deficiency impairs astrocytic lipophagy through ITGAV maturation.},
  author = {Xie XY, Wang L, Xie SQ, Zhou GF, Wen QX, Ma YL, Zhang QL, Yan XX, Luo B, Chen J, Song L, Chen X, Li CL, Pan QL, Liu Y, Xiang XJ, Chen GJ},
  journal = {Autophagy},
  year = {2026},
  pmid = {41376284},
  doi = {10.1080/15548627.2025.2601039},
  url = {https://pubmed.ncbi.nlm.nih.gov/41376284/},
}

@article{pmid41507800,
  title = {Analysis of high glucose injury using human induced pluripotent stem cell-derived kidney organoids.},
  author = {["Qian Z", "Yang D", "Li Y", "Dong R", "Da J", "Chen Y", "Zha Y"]},
  journal = {BMC nephrology},
  year = {2026},
  pmid = {41507800},
  doi = {10.1186/s12882-025-04566-6},
}

@article{pmid41747816,
  title = {Benzo[a]pyrene exacerbates atherosclerosis by upregulating SPP1 to promote macrophage inflammation and lipid dysregulation: An integrated network toxicology, RNA-seq, and experimental validation study.},
  author = {["Li R", "Zheng J", "Tang Y", "Liu A", "Liu J", "Cai S"]},
  journal = {Vascular pharmacology},
  year = {2026},
  pmid = {41747816},
  doi = {10.1016/j.vph.2026.107589},
}

@article{pmid41748556,
  title = {Nuclear Myosin 1 links genomic architecture to adipose tissue remodeling, metabolic inflammation and obesity in mice.},
  author = {["Khalaji S", "Venit T", "Luk\u00e1\u010dov\u00e1 Z", "Fambri V", "Shrestha R", "Kaluarachchi S", "Boitet M", "Fagny M", "Saldi G", "Percipalle P"]},
  journal = {Cell death & disease},
  year = {2026},
  pmid = {41748556},
  doi = {10.1038/s41419-026-08525-3},
}

@article{pmid41758068,
  title = {Carotid plaque macrophage burden and inflammatory lipid-associated macrophage markers predict secondary major adverse cardiovascular events after endarterectomy.},
  author = {["Prange K", "Bel-Bordes G", "Depuydt M", "Barlampas P", "Reif M", "Gr\u00f6nloh M", "Kempkes R", "Griffith G", "van Roomen C", "Zhu Y"]},
  journal = {European heart journal},
  year = {2026},
  pmid = {41758068},
  doi = {10.1093/eurheartj/ehag117},
}

@article{pmid41795330,
  title = {Pregnane X receptor antagonist MI-891 reduces hepatic triglycerides in PXR-CAR-CYP3A4/3A7-humanized mice.},
  author = {["Dohnalov\u00e1 K", "Kamaraj R", "Ambro\u017e M", "Kl\u00edma K", "Chalupsk\u00fd K", "Bajnokov\u00e1 M", "Mejdrov\u00e1 I", "\u0160kach K", "Hricov\u00e1 J", "La\u0161t\u016fvkov\u00e1 H"]},
  journal = {Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year = {2026},
  pmid = {41795330},
  doi = {10.1016/j.biopha.2026.119168},
}

@article{pmid41801037,
  title = {African swine fever virus hijacks lipolysis induced by chaperone-mediated autophagy to upregulate fatty acid β-oxidation and promote viral replication.},
  author = {["Yang X", "Xiong X", "Liu H", "Wen X", "Shi X", "Ma H", "Wang R", "Cao W", "Yang F", "Ru Y"]},
  journal = {mBio},
  year = {2026},
  pmid = {41801037},
  doi = {10.1128/mbio.03368-25},
}

@article{pmid41810751,
  title = {Lipophagy fuels phosphatidylcholine synthesis for Newcastle disease virus replication.},
  author = {["Yang M", "Chen J", "Su X", "Kan X", "Tan L", "Song C", "Qiu X", "Liao Y", "Yu S", "Ding C"]},
  journal = {Autophagy},
  year = {2026},
  pmid = {41810751},
  doi = {10.1080/15548627.2026.2642980},
}

@article{pmid41827192,
  title = {Serum Perilipin-2 as a Novel Biomarker for Obstructive Sleep Apnea: Association with Hypoxic Burden and Disease Severity.},
  author = {Sagcan G, Uzun H},
  journal = {Journal of clinical medicine},
  year = {2026},
  pmid = {41827192},
  doi = {10.3390/jcm15051776},
  url = {https://pubmed.ncbi.nlm.nih.gov/41827192/},
}

@article{pmid41831570,
  title = {Epithelial-Mesenchymal Transition Shapes the Lipotoxic Response of Colon Cancer Cells to Palmitic Acid.},
  author = {Vari F, Serra I, Bisconti E, Stanca E, Raffo-Romero A, Mehenni S, Zirem Y, Vergara D, Fournier I, Giudetti AM, Salzet M},
  journal = {Molecular & cellular proteomics : MCP},
  year = {2026},
  pmid = {41831570},
  doi = {10.1016/j.mcpro.2026.101554},
  url = {https://pubmed.ncbi.nlm.nih.gov/41831570/},
}

@article{pmid41841177,
  title = {Integrated Analysis of Metabolomics and Proteomics Reveals the Potential Mechanism of Lung Injury Induced by Di(2-Ethylhexyl) Phthalate.},
  author = {["Wu S", "Wang B", "Zhang N", "Feng C", "Wang H", "Zheng Q", "Kang R", "Niu X", "Wang X", "Guo X"]},
  journal = {Journal of applied toxicology : JAT},
  year = {2026},
  pmid = {41841177},
  doi = {10.1002/jat.70153},
}

@article{pmid41871815,
  title = {Novel mechanisms of dietary folic acid in improving hepatopancreas health of grass carp (Ctenopharyngodon idellus): the perspectives of autophagy and DNA methylation.},
  author = {Wang Y, Feng L, Dan Jiang W, Wu P, Liu Y, Ma YB, Zhang HY, Ren HM, Jin XW, Zhou XQ},
  journal = {The Journal of nutritional biochemistry},
  year = {2026},
  pmid = {41871815},
  doi = {10.1016/j.jnutbio.2026.110350},
  url = {https://pubmed.ncbi.nlm.nih.gov/41871815/},
}

@article{pmid41888110,
  title = {PCDHGC3 silencing promotes clear cell renal cell carcinoma metastasis via mTOR/HIF2α activation, lipid metabolism rewiring, and ferroptosis evasion.},
  author = {Celada L, Cubiella T, San-Juan-Guardado J, Suárez-Priede Á, Gómez-Suárez N, Salerno L, Murias E, Da Silva Torres M, Weiner JA, Herrada-Manchón H, Fernández MA, Chiara MD},
  journal = {Cell death & disease},
  year = {2026},
  pmid = {41888110},
  doi = {10.1038/s41419-026-08643-y},
  url = {https://pubmed.ncbi.nlm.nih.gov/41888110/},
}

@article{pmid41897862,
  title = {Transcriptomic Analysis of High and Low Lipid Droplet Deposition Subpopulations of Chicken Preadipocytes Based on SSC Sorting.},
  author = {Wang B, Li Y, Wang Y, Chen J, Wang J, Li X, Li Z},
  journal = {Animals : an open access journal from MDPI},
  year = {2026},
  pmid = {41897862},
  doi = {10.3390/ani16060885},
  url = {https://pubmed.ncbi.nlm.nih.gov/41897862/},
}

@article{pmid41897862,
  title = {Transcriptomic Analysis of High and Low Lipid Droplet Deposition Subpopulations of Chicken Preadipocytes Based on SSC Sorting.},
  author = {Wang B, Li Y, Wang Y, Chen J, Wang J et al.},
  journal = {Animals (Basel)},
  year = {2026},
  pmid = {41897862},
  doi = {doi: 10.3390/ani16060885},
  url = {https://pubmed.ncbi.nlm.nih.gov/41897862/},
}

@article{pmid39984825,
  title = {FTO inhibition mitigates high-fat diet-induced metabolic disturbances and cognitive decline in SAMP8 mice.},
  author = {["Irisarri A", "Corral A", "Perez-Salvador N", "Bellver-Sanchis A", "Ribalta-Vilella M", "Bentanachs R", "Alegret M", "Laguna J", "Barroso E", "Palomer X"]},
  journal = {Molecular medicine (Cambridge, Mass.)},
  year = {2025},
  pmid = {39984825},
  doi = {10.1186/s10020-025-01126-4},
}

@article{pmid40617356,
  title = {Repurposing daclatasvir for MASLD Therapy-A promising step forward with challenges ahead.},
  author = {["Pirola C"]},
  journal = {Journal of lipid research},
  year = {2025},
  pmid = {40617356},
  doi = {10.1016/j.jlr.2025.100857},
}

@article{pmid41039597,
  title = {Microglial glycolytic reprogramming in alzheimer's disease: association with impaired phagocytic function and altered vascular proximity.},
  author = {["Lu N", "Jin Z", "Liu N", "Zhu C", "Wei H", "Xu Q"]},
  journal = {Journal of neuroinflammation},
  year = {2025},
  pmid = {41039597},
  doi = {10.1186/s12974-025-03546-9},
}

@article{pmid38773347,
  title = {Glycolytic enzyme PFKL governs lipolysis by promoting lipid droplet-mitochondria tethering to enhance β-oxidation and tumor cell proliferation.},
  author = {Meng Y, Guo D, Lin L, Zhao H, Xu W, Luo S, Jiang X, Li S, He X, Zhu R},
  journal = {Nat Metab},
  year = {2024},
  pmid = {38773347},
  doi = {10.1038/s42255-024-01047-2},
  url = {https://pubmed.ncbi.nlm.nih.gov/38773347},
}

@article{pmid39033779,
  title = {Lipid accumulation drives cellular senescence in dopaminergic neurons.},
  author = {Russo T, Riessland M},
  journal = {Aging (Albany NY)},
  year = {2024},
  pmid = {39033779},
  doi = {10.18632/aging.206030},
  url = {https://pubmed.ncbi.nlm.nih.gov/39033779},
}

@article{pmid37494933,
  title = {Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation.},
  author = {Roberts MA, Deol KK, Mathiowetz AJ, Lange M, Leto DE, Stevenson J, Hashemi SH, Morgens DW, Easter E, Heydari K},
  journal = {Dev Cell},
  year = {2023},
  pmid = {37494933},
  doi = {10.1016/j.devcel.2023.07.001},
  url = {https://pubmed.ncbi.nlm.nih.gov/37494933},
}

@article{pmid37605362,
  title = {Ferroptosis of Microglia in Aging Human White Matter Injury.},
  author = {Adeniyi PA, Gong X, MacGregor E, Degener-O'Brien K, McClendon E, Garcia M, Romero O, Russell J, Srivastava T, Miller J, Keene CD, Back SA},
  journal = {Annals of neurology},
  year = {2023},
  pmid = {37605362},
  doi = {10.1002/ana.26770},
  url = {https://pubmed.ncbi.nlm.nih.gov/37605362/},
}

@article{pmid34312912,
  title = {Expression pattern of perilipins in human brain during aging and in Alzheimer's disease.},
  author = {["Conte M", "Medici V", "Malagoli D", "Chiariello A", "Cirrincione A", "Davin A", "Chikhladze M", "Vasuri F", "Legname G", "Ferrer I"]},
  journal = {Neuropathology and applied neurobiology},
  year = {2022},
  pmid = {34312912},
  doi = {10.1111/nan.12756},
}

@article{pmid36265491,
  title = {Comprehensive single-cell transcriptional profiling defines shared and unique epithelial injury responses during kidney fibrosis.},
  author = {Li H, Dixon EE, Wu H, Humphreys BD},
  journal = {Cell Metab},
  year = {2022},
  pmid = {36265491},
  doi = {10.1016/j.cmet.2022.09.026},
  url = {https://pubmed.ncbi.nlm.nih.gov/36265491},
}

@article{pmid33176578,
  title = {Targeting Mitochondria-Inflammation Circuit by β-Hydroxybutyrate Mitigates HFpEF.},
  author = {["Deng Y", "Xie M", "Li Q", "Xu X", "Ou W", "Zhang Y", "Xiao H", "Yu H", "Zheng Y", "Liang Y"]},
  journal = {Circulation research},
  year = {2021},
  pmid = {33176578},
  doi = {10.1161/CIRCRESAHA.120.317933},
}

@article{pmid33462313,
  title = {Radiolysis generates a complex organosynthetic chemical network.},
  author = {["Adam Z", "Fahrenbach A", "Jacobson S", "Kacar B", "Zubarev D"]},
  journal = {Scientific reports},
  year = {2021},
  pmid = {33462313},
  doi = {10.1038/s41598-021-81293-6},
}

@article{pmid32405032,
  title = {Telehealth in urology after the COVID-19 pandemic.},
  author = {["Gadzinski A", "Ellimoottil C"]},
  journal = {Nature reviews. Urology},
  year = {2020},
  pmid = {32405032},
  doi = {10.1038/s41585-020-0336-6},
}

@article{pmid31061494,
  title = {A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.},
  author = {["Van Hove H", "Martens L", "Scheyltjens I", "De Vlaminck K", "Pombo Antunes A", "De Prijck S", "Vandamme N", "De Schepper S", "Van Isterdael G", "Scott C"]},
  journal = {Nature neuroscience},
  year = {2019},
  pmid = {31061494},
  doi = {10.1038/s41593-019-0393-4},
}