% Bibliography for hypothesis h-3d545f4e
% Title: Targeted Butyrate Supplementation for Microglial Phenotype Modulation
% Generated: 2026-04-28T18:44:04Z

@article{pmid40637840,
  title = {Therapeutic strategies for hypertension: exploring the role of microbiota-derived short-chain fatty acids in kidney physiology and development.},
  author = {Tortelote GG},
  journal = {Pediatr Nephrol},
  year = {2026},
  pmid = {40637840},
  doi = {doi: 10.1007/s00467-025-06883-2},
  url = {https://pubmed.ncbi.nlm.nih.gov/40637840/},
}

@article{pmid41638192,
  title = {Gut microbiota-derived isovaleric acid alleviates atrial fibrillation by suppressing GSDME-dependent pyroptosis.},
  author = {Ding N, Wu H, Hua Y, Hua R, Li B, Xie Y, Xiong Y, Bai T, Shi X, Shen T, Liu P, Liu J, Yang X, Xu Y, Meng Z, Lan B, Zhou J, Liu B, Shyy JY, Yuan Z, Wu Y, Li T},
  journal = {Cell metabolism},
  year = {2026},
  pmid = {41638192},
  doi = {10.1016/j.cmet.2025.12.017},
  url = {https://pubmed.ncbi.nlm.nih.gov/41638192/},
}

@article{pmid41655800,
  title = {Xin-Jia-Tong-Xie-Yao-Fang restores the intestinal barrier to alleviate irritable bowel syndrome via microbial butyrate mediated PI3K/Akt pathway suppression.},
  author = {Zhu J, Yang L, Fang Z, Chen J, Fu R, Liu S, Chen M},
  journal = {Microbial pathogenesis},
  year = {2026},
  pmid = {41655800},
  doi = {10.1016/j.micpath.2026.108344},
  url = {https://pubmed.ncbi.nlm.nih.gov/41655800/},
}

@article{pmid41680408,
  title = {Cranberry extract-supplemented microbiota effluents enhance intestinal barrier integrity via mucin production and antimicrobial activity in murine organoids.},
  author = {Cattero V, Mayer T, Veilleux A, Roussel C, Desjardins Y},
  journal = {Scientific reports},
  year = {2026},
  pmid = {41680408},
  doi = {10.1038/s41598-026-39008-2},
  url = {https://pubmed.ncbi.nlm.nih.gov/41680408/},
}

@article{pmid41754753,
  title = {Qingfei Tongluo Jiedu Formula Regulates M2 Macrophage Polarization via the Butyric Acid-GPR109A-MAPK Pathway for the Treatment of Mycoplasma pneumoniae Pneumonia.},
  author = {Liu Z, Fan Q, Sun R, Jiang Y},
  journal = {Pharmaceuticals (Basel, Switzerland)},
  year = {2026},
  pmid = {41754753},
  doi = {10.3390/ph19020212},
  url = {https://pubmed.ncbi.nlm.nih.gov/41754753/},
}

@article{pmid41816355,
  title = {Periodontitis promotes intestinal inflammation through gut microbiota-mediated suppression of GPR109A.},
  author = {Wang X, Xu Z, Yao Y, Jia H, Du M, Wang S, Yan F, Li L},
  journal = {Frontiers in cellular and infection microbiology},
  year = {2026},
  pmid = {41816355},
  doi = {10.3389/fcimb.2026.1761932},
  url = {https://pubmed.ncbi.nlm.nih.gov/41816355/},
}

@article{pmid41882026,
  title = {GPR109a-AMPK axis mediates the Attenuation of uric acid-induced M1 macrophage polarization by β-hydroxybutyrate from Lacticaseibacillus rhamnosus M2b.},
  author = {Du M, He Y, Zhu Y, Chen W, Chen X, Yang D, Yang Q, Zhang B, Sun Y},
  journal = {Scientific reports},
  year = {2026},
  pmid = {41882026},
  doi = {10.1038/s41598-026-39746-3},
  url = {https://pubmed.ncbi.nlm.nih.gov/41882026/},
}

@article{pmid41889514,
  title = {Hydroxycarboxylic acid receptor 2 (GPR109A) and retinopathies: pathways and prospects.},
  author = {Lester J, Amamoo R, Thounaojam MC, Martin PM, Jadeja RN},
  journal = {Frontiers in medicine},
  year = {2026},
  pmid = {41889514},
  doi = {10.3389/fmed.2026.1776648},
  url = {https://pubmed.ncbi.nlm.nih.gov/41889514/},
}

@article{pmid40305364,
  title = {Not Just an Alternative Energy Source: Diverse Biological Functions of Ketone Bodies and Relevance of HMGCS2 to Health and Disease.},
  author = {Suresh VV, Sivaprakasam S, Bhutia YD, Prasad PD, Thangaraju M, Ganapathy V},
  journal = {Biomolecules},
  year = {2025},
  pmid = {40305364},
  doi = {10.3390/biom15040580},
  url = {https://pubmed.ncbi.nlm.nih.gov/40305364/},
}

@article{pmid40319428,
  title = {Chaperone-mediated autophagy, heat shock protein 70, and serotonin: novel targets of beta-hydroxybutyrate in HFFD/LPS-induced sporadic Alzheimer's disease model.},
  author = {["Mohamed R", "Abdallah D", "El-Abhar H"]},
  journal = {Inflammopharmacology},
  year = {2025},
  pmid = {40319428},
  doi = {10.1007/s10787-025-01754-6},
}

@article{pmid41421649,
  title = {Exercise-induced β-hydroxybutyrate contributes to cognitive improvement in aging mice.},
  author = {Wang L, Mao L, Zhu D, Li K, Gao H, Zhou M, Wu J, Yang D, Wang Z, Wang W, Guo Y, Xu Y, Chen P, Xiao W},
  journal = {Journal of sport and health science},
  year = {2025},
  pmid = {41421649},
  doi = {10.1016/j.jshs.2025.101113},
  url = {https://pubmed.ncbi.nlm.nih.gov/41421649/},
}

@article{pmid36771231,
  title = {β-Hydroxybutyrate Regulates Activated Microglia to Alleviate Neurodegenerative Processes in Neurological Diseases: A Scoping Review.},
  author = {Jayashankar SS, Tajul Arifin K, Nasaruddin ML},
  journal = {Nutrients},
  year = {2023},
  pmid = {36771231},
  doi = {10.3390/nu15030524},
  url = {https://pubmed.ncbi.nlm.nih.gov/36771231/},
}

@article{pmid34452635,
  title = {Bacterial factors required for Streptococcus pneumoniae coinfection with influenza A virus.},
  author = {Chen YY, Huang CT, Li SW, Pan YJ, Lin TL, Huang YY, Li TH, Yang YC, Gong YN, Hsieh YC},
  journal = {Journal of biomedical science},
  year = {2021},
  pmid = {34452635},
  doi = {10.1186/s12929-021-00756-0},
  url = {https://pubmed.ncbi.nlm.nih.gov/34452635/},
}

@article{pmid32273329,
  title = {Serum neuronal exosomes predict and differentiate Parkinson's disease from atypical parkinsonism.},
  author = {Jiang C, Hopfner F, Katsikoudi A, Hein R, Catli C, Evetts S, Huang Y, Wang H, Ryder JW, Kuhlenbaeumer G, Deuschl G, Padovani A, Berg D, Borroni B, Hu MT, Davis JJ, Tofaris GK},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year = {2020},
  pmid = {32273329},
  doi = {10.1136/jnnp-2019-322588},
  url = {https://pubmed.ncbi.nlm.nih.gov/32273329/},
}

@article{pmid33028628,
  title = {Adapting Drosophila melanogaster Cell Lines to Serum-Free Culture Conditions.},
  author = {Luhur A, Mariyappa D, Klueg KM, Buddika K, Tennessen JM, Zelhof AC},
  journal = {G3 (Bethesda, Md.)},
  year = {2020},
  pmid = {33028628},
  doi = {10.1534/g3.120.401769},
  url = {https://pubmed.ncbi.nlm.nih.gov/33028628/},
}

@article{pmid33154920,
  title = {Massive Hemoptysis and Recurrent Infective Endocarditis in Intravenous Drug user: A Case Report.},
  author = {Almutairi MD, El-Ghoneimy YA, Alghamdi AO, Alkhamis HA, Altayyar ZA, Houbani KM},
  journal = {Journal of the Saudi Heart Association},
  year = {2020},
  pmid = {33154920},
  doi = {10.37616/2212-5043.1041},
  url = {https://pubmed.ncbi.nlm.nih.gov/33154920/},
}

@article{pmid33273115,
  title = {Face masks considerably reduce COVID-19 cases in Germany.},
  author = {Mitze T, Kosfeld R, Rode J, Wälde K},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year = {2020},
  pmid = {33273115},
  doi = {10.1073/pnas.2015954117},
  url = {https://pubmed.ncbi.nlm.nih.gov/33273115/},
}

@article{pmid31261156,
  title = {Predictive Role of High Blood Pressure for the Incidence of Metabolic Syndrome.},
  author = {Presta V, Miceli F, Tocci G},
  journal = {Cardiology},
  year = {2019},
  pmid = {31261156},
  doi = {10.1159/000500321},
  url = {https://pubmed.ncbi.nlm.nih.gov/31261156/},
}

@article{pmid31420438,
  title = {Surgical approach to a left-sided gallbladder.},
  author = {Pereira R, Perera M, Roberts M, Avramovic J},
  journal = {BMJ case reports},
  year = {2019},
  pmid = {31420438},
  doi = {10.1136/bcr-2019-230681},
  url = {https://pubmed.ncbi.nlm.nih.gov/31420438/},
}

@article{pmid31578143,
  title = {Comparison of tension band wiring and other tibial tuberosity advancement techniques for cranial cruciate ligament repair: an experimental study.},
  author = {McCartney W, Ober C, Benito M, MacDonald B},
  journal = {Acta veterinaria Scandinavica},
  year = {2019},
  pmid = {31578143},
  doi = {10.1186/s13028-019-0481-1},
  url = {https://pubmed.ncbi.nlm.nih.gov/31578143/},
}

@article{pmid31591459,
  title = {Metformin use and risk of gastric adenocarcinoma in a Swedish population-based cohort study.},
  author = {Zheng J, Xie SH, Santoni G, Lagergren J},
  journal = {British journal of cancer},
  year = {2019},
  pmid = {31591459},
  doi = {10.1038/s41416-019-0598-z},
  url = {https://pubmed.ncbi.nlm.nih.gov/31591459/},
}

@article{pmid29540330,
  title = {Pulseq-Graphical Programming Interface: Open source visual environment for prototyping pulse sequences and integrated magnetic resonance imaging algorithm development.},
  author = {Ravi KS, Potdar S, Poojar P, Reddy AK, Kroboth S, Nielsen JF, Zaitsev M, Venkatesan R, Geethanath S},
  journal = {Magnetic resonance imaging},
  year = {2018},
  pmid = {29540330},
  doi = {10.1016/j.mri.2018.03.008},
  url = {https://pubmed.ncbi.nlm.nih.gov/29540330/},
}

@article{pmid30059672,
  title = {Role of vitamin D in pregnancy and Toll-like receptor pathway.},
  author = {Momentti AC, Estadella D, Pellegrini Pisani L},
  journal = {Steroids},
  year = {2018},
  pmid = {30059672},
  doi = {10.1016/j.steroids.2018.07.009},
  url = {https://pubmed.ncbi.nlm.nih.gov/30059672/},
}

@article{pmid30154787,
  title = {Butyrate and Dietary Soluble Fiber Improve Neuroinflammation Associated With Aging in Mice.},
  author = {Matt SM, Allen JM, Lawson MA, Mailing LJ, Woods JA, Johnson RW},
  journal = {Frontiers in immunology},
  year = {2018},
  pmid = {30154787},
  doi = {10.3389/fimmu.2018.01832},
  url = {https://pubmed.ncbi.nlm.nih.gov/30154787/},
}

@article{pmid28578305,
  title = {Multiple supratentorial subependymomas causing obstructive hydrocephalus.},
  author = {Schroeder J, LeFever D, Entezami P, Mrak RE},
  journal = {BMJ case reports},
  year = {2017},
  pmid = {28578305},
  doi = {10.1136/bcr-2016-215625},
  url = {https://pubmed.ncbi.nlm.nih.gov/28578305/},
}

@article{pmid25595674,
  title = {Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson's disease models are mediated by GPR109A-dependent mechanisms.},
  author = {Fu SP, Wang JF, Xue WJ, Liu HM, Liu BR, Zeng YL, Li SN, Huang BX, Lv QK, Wang W, Liu JX},
  journal = {Journal of neuroinflammation},
  year = {2015},
  pmid = {25595674},
  doi = {10.1186/s12974-014-0230-3},
  url = {https://pubmed.ncbi.nlm.nih.gov/25595674/},
}

@article{pmid25329911,
  title = {Upregulation of GPR109A in Parkinson's disease.},
  author = {Wakade C, Chong R, Bradley E, Thomas B, Morgan J},
  journal = {PloS one},
  year = {2014},
  pmid = {25329911},
  doi = {10.1371/journal.pone.0109818},
  url = {https://pubmed.ncbi.nlm.nih.gov/25329911/},
}

@article{pmid21499426,
  title = {Brain delivery of valproic acid via intranasal administration of nanostructured lipid carriers: in vivo pharmacodynamic studies using rat electroshock model.},
  author = {Eskandari S, Varshosaz J, Minaiyan M, Tabbakhian M},
  journal = {International journal of nanomedicine},
  year = {2011},
  pmid = {21499426},
  doi = {10.2147/IJN.S15881},
  url = {https://pubmed.ncbi.nlm.nih.gov/21499426/},
}

@article{pmid17554232,
  title = {[Niacin in therapy].},
  author = {Nagalski Andrzej; Bryła Jadwiga},
  journal = {Postepy higieny i medycyny doswiadczalnej (Online)},
  year = {2007},
  pmid = {17554232},
  url = {https://pubmed.ncbi.nlm.nih.gov/17554232/},
}