% Bibliography for hypothesis h-38292315
% Title: Metabolic Reprogramming via Microglial Glycolysis Inhibition
% Generated: 2026-04-28T14:06:41Z

@article{pmid41387352,
  title = {HK1 and HK2 Beyond Glycolysis: Mitochondrial Interactions and Dual Roles in Metabolism and Cell Fate.},
  author = {Pesce NA, Seminara G, Giarrusso G, Tomasello MF},
  journal = {Adv Biol (Weinh)},
  year = {2026},
  pmid = {41387352},
  doi = {10.1002/adbi.202500472},
  url = {https://pubmed.ncbi.nlm.nih.gov/41387352},
}

@article{pmid41520557,
  title = {Bergenin attenuates traumatic brain injury via inhibition of microglial PFKFB3-driven glycolytic-inflammatory crosstalk.},
  author = {Sun B, Zhang A, Feng S, Jamali AW, Jia Z, Xu Y, Wang Z, Zhao J, Sun G, Liu L},
  journal = {Int Immunopharmacol},
  year = {2026},
  pmid = {41520557},
  doi = {10.1016/j.intimp.2026.116181},
  url = {https://pubmed.ncbi.nlm.nih.gov/41520557},
}

@article{pmid41569027,
  title = {Modulation of Aerobic Glycolysis Genes During the Progression of Retinitis Pigmentosa.},
  author = {["Adani E", "Villa Vasquez S", "Lovino M", "Bighinati A", "Cappellino L", "D'Alessandro S", "Kalatzis V", "Marigo V"]},
  journal = {Investigative ophthalmology & visual science},
  year = {2026},
  pmid = {41569027},
  doi = {10.1167/iovs.67.1.49},
}

@article{pmid41677100,
  title = {Mitophagy bridges glucose metabolism, inflammation and neuroprotection in astrocytes.},
  author = {["Hakansson H", "Howden J", "Kittler J"]},
  journal = {Autophagy},
  year = {2026},
  pmid = {41677100},
  doi = {10.1080/15548627.2026.2623987},
}

@article{pmid41897347,
  title = {Investigating the Effect and Mechanism of Protocatechuic Aldehyde on Vascular Dementia Based on Multi-Omics Approach.},
  author = {["Xiao T", "Tao J", "Tan J", "Yi X", "Wang Z", "Duan X"]},
  journal = {Biomolecules},
  year = {2026},
  pmid = {41897347},
  doi = {10.3390/biom16030411},
}

@article{pmid41899603,
  title = {Crosstalk Between },
  author = {["Ren Y", "Tang D", "Ding X", "He M"]},
  journal = {Cancers},
  year = {2026},
  pmid = {41899603},
  doi = {10.3390/cancers18061002},
}

@article{pmid41900891,
  title = {Quercetin Attenuates Iron Overload-Induced Renal Injury via Activating Nrf2/xCT/GPX4 Signaling to Inhibit Ferroptosis.},
  author = {["Wang X", "Li W", "Yuan W", "Wei Z", "Yang Z", "Zhang Z", "Sun Z", "Ji G", "Hu H"]},
  journal = {Life (Basel, Switzerland)},
  year = {2026},
  pmid = {41900891},
  doi = {10.3390/life16030372},
}

@article{pmid41902192,
  title = {STING Degradation by PRRSV Activates HK2-Mediated Glycolysis to Facilitate Viral Replication.},
  author = {Luo L, Zhou L, Gao X, Li Y, Zhou H, Li Y, Zhang Z},
  journal = {Viruses},
  year = {2026},
  pmid = {41902192},
  doi = {10.3390/v18030284},
  url = {https://pubmed.ncbi.nlm.nih.gov/41902192/},
}

@article{pmid41905095,
  title = {Duzhong-Gegen formula ameliorated hyperuricemia by enhancing renal uric acid excretion through activation of SIRT1.},
  author = {Wang L, Gan Y, Huang J, Long L, Li S, Wang X, Xie T, Zhu Q},
  journal = {Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year = {2026},
  pmid = {41905095},
  doi = {10.1016/j.phymed.2026.158091},
  url = {https://pubmed.ncbi.nlm.nih.gov/41905095/},
}

@article{pmid41916119,
  title = {FOXP1 deficiency exacerbates cellular senescence in PM},
  author = {["Chen H", "Zhan Z", "Lu M", "Li D", "Peng J", "Chen L", "Yi B", "Huang Z"]},
  journal = {Ecotoxicology and environmental safety},
  year = {2026},
  pmid = {41916119},
  doi = {10.1016/j.ecoenv.2026.120071},
}

@article{pmid41921767,
  title = {Erchen decoction and its active flavonoids hesperidin and quercetin alleviate high-fat diet-induced neuroinflammation by targeting HK2-mediated microglial glycolysis.},
  author = {Zheng M, Yang K, Ma Y, Suo W, Li J, Huang Y, Gao P, Liu K, Zhang Y, Liu H, Guan L, Yan F, Xu J, Liu T, Xu J},
  journal = {Journal of ethnopharmacology},
  year = {2026},
  pmid = {41921767},
  doi = {10.1016/j.jep.2026.121603},
  url = {https://pubmed.ncbi.nlm.nih.gov/41921767/},
}

@article{pmid41924308,
  title = {Multifunctional Engineered Metal-Organic Frameworks as Targeted Protein Degraders for Augmenting Cancer Therapy via Hexokinase 2 Degradation and Provoking Cuproptosis.},
  author = {["Li S", "Liu R", "Zhang Q", "Sun J", "Hao H", "Yao C", "Yan L", "Yang D", "Liu D"]},
  journal = {Research (Washington, D.C.)},
  year = {2026},
  pmid = {41924308},
  doi = {10.34133/research.1217},
}

@article{pmid39987285,
  title = {Glucose Metabolic Reprogramming in Microglia: Implications for Neurodegenerative Diseases and Targeted Therapy.},
  author = {Fang M, Zhou Y, He K, Lu Y, Tao F, Huang H},
  journal = {Mol Neurobiol},
  year = {2025},
  pmid = {39987285},
  doi = {10.1007/s12035-025-04775-y},
  url = {https://pubmed.ncbi.nlm.nih.gov/39987285},
}

@article{pmid40911376,
  title = {Deficiency of Microglial Hv1 Protects Against Lipopolysaccharide-Induced Neuroinflammation via the NF-κB Signaling Pathway and HIF1α-Mediated Metabolic Reprogramming.},
  author = {Sun L, Wang X, Guan S, Zhang P, Chen D, Luo T},
  journal = {FASEB J},
  year = {2025},
  pmid = {40911376},
  doi = {10.1096/fj.202402271RRR},
  url = {https://pubmed.ncbi.nlm.nih.gov/40911376},
}

@article{pmid38904014,
  title = {The PI3K/Akt Pathway and Glucose Metabolism: A Dangerous Liaison in Cancer.},
  author = {Fontana F, Giannitti G, Marchesi S, Limonta P},
  journal = {Int J Biol Sci},
  year = {2024},
  pmid = {38904014},
  doi = {10.7150/ijbs.89942},
  url = {https://pubmed.ncbi.nlm.nih.gov/38904014},
}

@article{pmid39217289,
  title = {AST-120 alleviates renal ischemia-reperfusion injury by inhibiting HK2-mediated glycolysis.},
  author = {Zhou J, Zhang J, Xu F, Gao H, Wang L, Zhao Y, Li K},
  journal = {Mol Med},
  year = {2024},
  pmid = {39217289},
  doi = {10.1186/s10020-024-00902-y},
  url = {https://pubmed.ncbi.nlm.nih.gov/39217289},
}

@article{pmid37443289,
  title = {STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2.},
  author = {Zhang L, Jiang C, Zhong Y, Sun K, Jing H, Song J, Xie J, Zhou Y, Tian M, Zhang C, Sun X, Wang S, Cheng X, Zhang Y, Wei W, Li X, Fu B, Feng P, Wu B, Shu HB, Zhang J},
  journal = {Nature cell biology},
  year = {2023},
  pmid = {37443289},
  doi = {10.1038/s41556-023-01185-x},
  url = {https://pubmed.ncbi.nlm.nih.gov/37443289/},
}

@article{pmid37463576,
  title = {Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis.},
  author = {Rho H, Terry AR, Chronis C, Hay N},
  journal = {Cell Metab},
  year = {2023},
  pmid = {37463576},
  doi = {10.1016/j.cmet.2023.06.013},
  url = {https://pubmed.ncbi.nlm.nih.gov/37463576},
}

@article{pmid35246504,
  title = {Zeb1-induced metabolic reprogramming of glycolysis is essential for macrophage polarization in breast cancer.},
  author = {Jiang H, Wei H, Wang H, Wang Z, Li J, Ou Y, Xiao X, Wang W, Chang A, Sun W, Zhao L, Yang S},
  journal = {Cell death & disease},
  year = {2022},
  pmid = {35246504},
  doi = {10.1038/s41419-022-04632-z},
  url = {https://pubmed.ncbi.nlm.nih.gov/35246504/},
}

@article{pmid36419136,
  title = {UBR7 inhibits HCC tumorigenesis by targeting Keap1/Nrf2/Bach1/HK2 and glycolysis.},
  author = {Zhao L, Kang M, Liu X, Wang Z, Wang Y, Chen H, Liu W, Liu S, Li B, Li C, Chang A, Tang B},
  journal = {Journal of experimental & clinical cancer research : CR},
  year = {2022},
  pmid = {36419136},
  doi = {10.1186/s13046-022-02528-6},
  url = {https://pubmed.ncbi.nlm.nih.gov/36419136/},
}

@article{pmid31168067,
  title = {Lower excitatory synaptic gene expression in orbitofrontal cortex and striatum in an initial study of subjects with obsessive compulsive disorder.},
  author = {["Piantadosi S", "Chamberlain B", "Glausier J", "Lewis D", "Ahmari S"]},
  journal = {Molecular psychiatry},
  year = {2021},
  pmid = {31168067},
  doi = {10.1038/s41380-019-0431-3},
}

@article{pmid33446494,
  title = {UK will miss healthy ageing targets without urgent action, inquiry concludes},
  author = {Gareth Iacobucci},
  journal = {BMJ (Clinical research ed.)},
  year = {2021},
  pmid = {33446494},
  doi = {10.1136/bmj.n125},
}

@article{pmid34624224,
  title = {Hallmarks of response, resistance, and toxicity to immune checkpoint blockade.},
  author = {["Morad G", "Helmink B", "Sharma P", "Wargo J"]},
  journal = {Cell},
  year = {2021},
  pmid = {34624224},
  doi = {10.1016/j.cell.2021.09.020},
}

@article{pmid31395865,
  title = {Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution},
  author = {["Kircher M", "Xiong C", "Martin B", "Schubach M", "Inoue F", "Bell R", "Costello J", "Shendure J", "Ahituv N"]},
  journal = {Nature Communications},
  year = {2019},
  pmid = {31395865},
  doi = {10.1038/s41467-019-11526-w},
}

@article{pmid31474370,
  title = {Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.},
  author = {["Martin J", "Chang C", "Boschetti G", "Ungaro R", "Giri M", "Grout J", "Gettler K", "Chuang L", "Nayar S", "Greenstein A"]},
  journal = {Cell},
  year = {2019},
  pmid = {31474370},
  doi = {10.1016/j.cell.2019.08.008},
}

@article{pmid30232389,
  title = {Child Weight Gain Trajectories Linked To Oral Microbiota Composition.},
  author = {["Craig S", "Blankenberg D", "Parodi A", "Paul I", "Birch L", "Savage J", "Marini M", "Stokes J", "Nekrutenko A", "Reimherr M"]},
  journal = {Scientific reports},
  year = {2018},
  pmid = {30232389},
  doi = {10.1038/s41598-018-31866-9},
}

@article{pmid27067241,
  title = {Validation of the Sexual Orientation Microaggression Inventory in Two Diverse Samples of LGBTQ Youth.},
  author = {["Swann G", "Minshew R", "Newcomb M", "Mustanski B"]},
  journal = {Archives of sexual behavior},
  year = {2016},
  pmid = {27067241},
  doi = {10.1007/s10508-016-0718-2},
}

@article{pmid26075878,
  title = {HK2/hexokinase-II integrates glycolysis and autophagy to confer cellular protection.},
  author = {Tan VP, Miyamoto S},
  journal = {Autophagy},
  year = {2015},
  pmid = {26075878},
  doi = {10.1080/15548627.2015.1042195},
  url = {https://pubmed.ncbi.nlm.nih.gov/26075878/},
}

@article{pmid26269185,
  title = {Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination.},
  author = {["Lau S", "Feng Y", "Chen H", "Luk H", "Yang W", "Li K", "Zhang Y", "Huang Y", "Song Z", "Chow W"]},
  journal = {Journal of virology},
  year = {2015},
  pmid = {26269185},
  doi = {10.1128/JVI.01048-15},
}

@article{pmid23890820,
  title = {Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat.},
  author = {["Atanur S", "Diaz A", "Maratou K", "Sarkis A", "Rotival M", "Game L", "Tschannen M", "Kaisaki P", "Otto G", "Ma M"]},
  journal = {Cell},
  year = {2013},
  pmid = {23890820},
  doi = {10.1016/j.cell.2013.06.040},
}