% Bibliography for hypothesis h-1a34778f
% Title: Senescent Cell Mitochondrial DNA Release
% Generated: 2026-04-28T19:17:11Z

@article{pmid41344577,
  title = {Decoding senescent drivers in Alzheimer's disease: From bench to bedside.},
  author = {["Zhou R", "Lin X", "Liao Z", "Lin J", "Zheng R", "Ni H", "Liu W", "Feng Z", "He Q", "Lin X"]},
  journal = {Ageing research reviews},
  year = {2026},
  pmid = {41344577},
  doi = {10.1016/j.arr.2025.102978},
}

@article{pmid41566049,
  title = {Past, present and future perspectives on the science of aging.},
  author = {Fabrisia Ambrosio; Maxim N Artyomov; Steven N Austad; Nir Barzilai; Juan Carlos Izpisua Belmonte; Daniel W Belsky; Bérénice A Benayoun; Anne Brunet; Handan Melike Dönertaş; Dena B Dubal; Evandro F Fang; Jerome N Feige; Linda P Fried; David Furman; Xu Gao; Vadim N Gladyshev; Vera Gorbunova; Myriam Gorospe; Jing-Dong J Han; Oskar Hansson; Eiji Hara; Steve Horvath; Nancy Y Ip; George A Kuchel; Matt Kaeberlein; Dudley W Lamming; Becca R Levy; Guang-Hui Liu; Jinkook Lee; Terrie E Moffitt; Tohru Minamino; Linda Partridge; Parminder Raina; Thomas A Rando; John W Rowe; Michal Schwartz; Andrew J Scott; Felipe Sierra; David A Sinclair; Charlotte E Teunissen; Bruno Vellas; Eric Verdin; Keenan A Walker; Ashley E Webb; Tony Wyss-Coray; Ming Xu; Jin-Tai Yu; Alex Zhavoronkov; Yahyah Aman; Anna Kriebs; Qingzhong Ren; Hannah Walters; Sebastien Thuault},
  journal = {Nature aging},
  year = {2026},
  pmid = {41566049},
  doi = {10.1038/s43587-025-01046-2},
}

@article{pmid41668757,
  title = {Stimuli-responsive nanoplatforms for precision activation of the STING pathway in cancer immunotherapy.},
  author = {["Bi D", "Yang X", "Wang Y", "Yong J", "Yang F", "Tan X", "Li Y", "Zheng D", "Li P"]},
  journal = {Frontiers in immunology},
  year = {2026},
  pmid = {41668757},
  doi = {10.3389/fimmu.2026.1714249},
}

@article{pmid40010204,
  title = {Role of NEIL1 in genome maintenance.},
  author = {["McCullough A", "Minko I", "Luzadder M", "Zuckerman J", "Vartanian V", "Jaruga P", "Dizdaroglu M", "Lloyd R"]},
  journal = {DNA repair},
  year = {2025},
  pmid = {40010204},
  doi = {10.1016/j.dnarep.2025.103820},
}

@article{pmid40080226,
  title = {Methodological influences on circulating cell-free-mitochondrial and nuclear DNA concentrations in response to chronic stress.},
  author = {["Daubermann C", "Herhaus B", "Neuberger E", "Simon P", "Petrowski K"]},
  journal = {Molecular biology reports},
  year = {2025},
  pmid = {40080226},
  doi = {10.1007/s11033-025-10369-7},
}

@article{pmid40203808,
  title = {Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway.},
  author = {["Lai P", "Liu L", "Bancaro N", "Troiani M", "Cal\u00ec B", "Li Y", "Chen J", "Singh P", "Arzola R", "Attanasio G"]},
  journal = {Immunity},
  year = {2025},
  pmid = {40203808},
  doi = {10.1016/j.immuni.2025.03.005},
}

@article{pmid40533746,
  title = {Exosomes as nanocarriers for brain-targeted delivery of therapeutic nucleic acids: advances and challenges.},
  author = {["Sanadgol N", "Abedi M", "Hashemzaei M", "Kamran Z", "Khalseh R", "Beyer C", "Voelz C"]},
  journal = {Journal of nanobiotechnology},
  year = {2025},
  pmid = {40533746},
  doi = {10.1186/s12951-025-03528-2},
}

@article{pmid40651559,
  title = {Apheresis for senescence: Targeting the senescence-associated secretory phenotype to delay aging and age-related diseases.},
  author = {["Akgun Y"]},
  journal = {Ageing research reviews},
  year = {2025},
  pmid = {40651559},
  doi = {10.1016/j.arr.2025.102832},
}

@article{pmid40902587,
  title = {Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer's disease.},
  author = {["Song Z", "Xie X", "Chen Y", "Zhang B", "Li X", "Yang Y", "Mo W", "Zhang J", "Xu D"]},
  journal = {Immunity},
  year = {2025},
  pmid = {40902587},
  doi = {10.1016/j.immuni.2025.07.024},
}

@article{pmid41199078,
  title = {Bionanoconjugates in Neurodegeneration: Peptide-Nanoparticle Alliances for Next-Generation Therapies.},
  author = {["Ranjitha V", "Kumar A", "Kaalappa P"]},
  journal = {Pharmaceutical research},
  year = {2025},
  pmid = {41199078},
  doi = {10.1007/s11095-025-03941-0},
}

@article{pmid38704604,
  title = {Antileukemic potential of methylated indolequinone MAC681 through immunogenic necroptosis and PARP1 degradation.},
  author = {["Orlikova-Boyer B", "Lorant A", "Gajulapalli S", "Cerella C", "Schnekenburger M", "Lee J", "Paik J", "Lee Y", "Siegel D", "Ross D"]},
  journal = {Biomarker research},
  year = {2024},
  pmid = {38704604},
  doi = {10.1186/s40364-024-00594-w},
}

@article{pmid38839958,
  title = {Senescent glia link mitochondrial dysfunction and lipid accumulation.},
  author = {["Byrns C", "Perlegos A", "Miller K", "Jin Z", "Carranza F", "Manchandra P", "Beveridge C", "Randolph C", "Chaluvadi V", "Zhang S"]},
  journal = {Nature},
  year = {2024},
  pmid = {38839958},
  doi = {10.1038/s41586-024-07516-8},
}

@article{pmid39039044,
  title = {mtDNA release promotes cGAS-STING activation and accelerated aging of postmitotic muscle cells.},
  author = {["Li Y", "Cui J", "Liu L", "Hambright W", "Gan Y", "Zhang Y", "Ren S", "Yue X", "Shao L", "Cui Y"]},
  journal = {Cell death & disease},
  year = {2024},
  pmid = {39039044},
  doi = {10.1038/s41419-024-06863-8},
}

@article{pmid39490400,
  title = {The cGAS-STING pathway drives neuroinflammation and neurodegeneration via cellular and molecular mechanisms in neurodegenerative diseases.},
  author = {Zhang Y, Zou M, Wu H, Zhu J, Jin T},
  journal = {Neurobiology of disease},
  year = {2024},
  pmid = {39490400},
  doi = {10.1016/j.nbd.2024.106710},
  url = {https://pubmed.ncbi.nlm.nih.gov/39490400/},
}

@article{pmid39548919,
  title = {Enhancing Radiofrequency Ablation for Hepatocellular Carcinoma: Nano-Epidrug Effects on Immune Modulation and Antigenicity Restoration.},
  author = {["Li X", "Liu Y", "Ke J", "Wang Z", "Han M", "Wang N", "Miao Q", "Shao B", "Zhou D", "Yan F"]},
  journal = {Advanced materials (Deerfield Beach, Fla.)},
  year = {2024},
  pmid = {39548919},
  doi = {10.1002/adma.202414365},
}

@article{pmid36964253,
  title = {Molecular mechanisms of mitochondrial DNA release and activation of the cGAS-STING pathway.},
  author = {["Kim J", "Kim H", "Chung J"]},
  journal = {Experimental & molecular medicine},
  year = {2023},
  pmid = {36964253},
  doi = {10.1038/s12276-023-00965-7},
}

@article{pmid37532932,
  title = {cGAS-STING drives ageing-related inflammation and neurodegeneration.},
  author = {Gulen MF, Samson N, Keller A, Schwabenland M, Liu C, Glück S, Thacker VV, Favre L, Mangeat B, Kroese LJ, Krimpenfort P, Prinz M, Ablasser A},
  journal = {Nature},
  year = {2023},
  pmid = {37532932},
  doi = {10.1038/s41586-023-06373-1},
  url = {https://pubmed.ncbi.nlm.nih.gov/37532932/},
}

@article{pmid37633968,
  title = {The cGAS-STING-YY1 axis accelerates progression of neurodegeneration in a mouse model of Parkinson's disease via LCN2-dependent astrocyte senescence.},
  author = {["Jiang S", "Tian T", "Yao H", "Xia X", "Wang C", "Cao L", "Hu G", "Du R", "Lu M"]},
  journal = {Cell death and differentiation},
  year = {2023},
  pmid = {37633968},
  doi = {10.1038/s41418-023-01216-y},
}

@article{pmid37688657,
  title = {Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures.},
  author = {Pandics T, Major D, Fazekas-Pongor V, Szarvas Z, Peterfi A, Mukli P, Gulej R, Ungvari A, Fekete M, Tompa A, Tarantini S, Yabluchanskiy A, Conley S, Csiszar A, Tabak AG, Benyo Z, Adany R, Ungvari Z},
  journal = {GeroScience},
  year = {2023},
  pmid = {37688657},
  doi = {10.1007/s11357-023-00913-3},
  url = {https://pubmed.ncbi.nlm.nih.gov/37688657/},
}

@article{pmid37821702,
  title = {Apoptotic stress causes mtDNA release during senescence and drives the SASP.},
  author = {["Victorelli S", "Salmonowicz H", "Chapman J", "Martini H", "Vizioli M", "Riley J", "Cloix C", "Hall-Younger E", "Machado Espindola-Netto J", "Jurk D"]},
  journal = {Nature},
  year = {2023},
  pmid = {37821702},
  doi = {10.1038/s41586-023-06621-4},
}

@article{pmid35394877,
  title = {STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy.},
  author = {Hinkle JT, Patel J, Panicker N, Karuppagounder SS, Biswas D, Belingon B, Chen R, Brahmachari S, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year = {2022},
  pmid = {35394877},
  doi = {10.1073/pnas.2118819119},
  url = {https://pubmed.ncbi.nlm.nih.gov/35394877/},
}

@article{pmid35575089,
  title = {Biological aging processes underlying cognitive decline and neurodegenerative disease.},
  author = {["Gonzales M", "Garbarino V", "Pollet E", "Palavicini J", "Kellogg D", "Kraig E", "Orr M"]},
  journal = {The Journal of clinical investigation},
  year = {2022},
  pmid = {35575089},
  doi = {10.1172/JCI158453},
}

@article{pmid33187730,
  title = {Signaling by cGAS-STING in Neurodegeneration, Neuroinflammation, and Aging.},
  author = {["Paul B", "Snyder S", "Bohr V"]},
  journal = {Trends in neurosciences},
  year = {2021},
  pmid = {33187730},
  doi = {10.1016/j.tins.2020.10.008},
}

@article{pmid33634751,
  title = {Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)},
  author = {["Klionsky D", "Abdel-Aziz A", "Abdelfatah S", "Abdellatif M", "Abdoli A", "Abel S", "Abeliovich H", "Abildgaard M", "Abudu Y", "Acevedo-Arozena A"]},
  journal = {Autophagy},
  year = {2021},
  pmid = {33634751},
  doi = {10.1080/15548627.2020.1797280},
}

@article{pmid31501588,
  title = {Ageing as a risk factor for neurodegenerative disease.},
  author = {["Hou Y", "Dan X", "Babbar M", "Wei Y", "Hasselbalch SG", "Croteau DL", "Bohr VA"]},
  journal = {Nature reviews. Neurology},
  year = {2020},
  pmid = {31501588},
  doi = {10.1038/s41582-019-0244-7},
  url = {https://pubmed.ncbi.nlm.nih.gov/31501588/},
}

@article{pmid33031745,
  title = {TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.},
  author = {Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D},
  journal = {Cell},
  year = {2020},
  pmid = {33031745},
  doi = {10.1016/j.cell.2020.09.020},
  url = {https://pubmed.ncbi.nlm.nih.gov/33031745},
}

@article{pmid33031745,
  title = {TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.},
  author = {Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D},
  journal = {Cell},
  year = {2020},
  pmid = {33031745},
}

@article{pmid29362479,
  title = {Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.},
  author = {["Galluzzi L", "Vitale I", "Aaronson S", "Abrams J", "Adam D", "Agostinis P", "Alnemri E", "Altucci L", "Amelio I", "Andrews D"]},
  journal = {Cell death and differentiation},
  year = {2018},
  pmid = {29362479},
  doi = {10.1038/s41418-017-0012-4},
}

@article{pmid28680756,
  title = {Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression.},
  author = {["Layer J", "Kronm\u00fcller M", "Quast T", "van den Boorn-Konijnenberg D", "Effern M", "Hinze D", "Althoff K", "Schramm A", "Westermann F", "Peifer M"]},
  journal = {Oncoimmunology},
  year = {2017},
  pmid = {28680756},
  doi = {10.1080/2162402X.2017.1320626},
}