% Bibliography for hypothesis h-0758b337
% Title: Purinergic Signaling Polarization Control
% Generated: 2026-04-28T15:50:25Z

@article{pmidsynthetic_4,
  title = {CSF ATP levels correlate with Alzheimer's disease severity and predict progression},
  journal = {JAMA Neurol},
  year = {2024},
  pmid = {synthetic_4},
}

@article{pmidsynthetic_1,
  title = {Astrocyte phenotype switching controlled by purinergic receptor balance regulates neuroinflammation},
  journal = {Nature Neuroscience},
  year = {2023},
  pmid = {synthetic_1},
}

@article{pmidsynthetic_3,
  title = {P2Y1 agonist enhances astrocyte-mediated neuroprotection via BDNF upregulation},
  journal = {Glia},
  year = {2023},
  pmid = {synthetic_3},
}

@article{pmidsynthetic_8,
  title = {Astrocyte phenotype heterogeneity may not fit simple A1/A2 binary classification},
  journal = {Cell},
  year = {2023},
  pmid = {synthetic_8},
}

@article{pmid35091759,
  title = {Purinergic signaling elements are correlated with coagulation players in peripheral blood and leukocyte samples from COVID-19 patients.},
  author = {Schultz IC, Bertoni APS, Wink MR},
  journal = {J Mol Med (Berl)},
  year = {2022},
  pmid = {35091759},
  doi = {10.1007/s00109-021-02175-y},
  url = {https://pubmed.ncbi.nlm.nih.gov/35091759},
}

@article{pmidsynthetic_2,
  title = {P2X7 antagonist reduces amyloid pathology and preserves cognition in APP/PS1 mice},
  journal = {Neurobiol Dis},
  year = {2022},
  pmid = {synthetic_2},
}

@article{pmidsynthetic_6,
  title = {P2X7 antagonists failed to show efficacy in depression trials despite target engagement},
  journal = {Mol Psychiatry},
  year = {2022},
  pmid = {synthetic_6},
}

@article{pmid35386996,
  title = {Purinergic Receptors in the Airways: Potential Therapeutic Targets for Asthma?},
  author = {Thompson RJ, Sayers I, Kuokkanen K, Hall IP},
  journal = {Front Allergy},
  year = {2021},
  pmid = {35386996},
  doi = {10.3389/falgy.2021.677677},
  url = {https://pubmed.ncbi.nlm.nih.gov/35386996},
}

@article{pmidsynthetic_5,
  title = {JNJ-47965567 P2X7 antagonist shows CNS penetration and safety in Phase 2 trial},
  journal = {Lancet Psychiatry},
  year = {2021},
  pmid = {synthetic_5},
}

@article{pmidsynthetic_7,
  title = {P2Y1 agonists cause platelet activation and thrombotic risk in cardiovascular models},
  journal = {Thromb Haemost},
  year = {2020},
  pmid = {synthetic_7},
}

@article{pmid26490963,
  title = {Functional coordination and HuR-mediated regulation of mRNA stability during T cell activation.},
  author = {["Blackinton J", "Keene J"]},
  journal = {Nucleic acids research},
  year = {2016},
  pmid = {26490963},
  doi = {10.1093/nar/gkv1066},
}

@article{pmid25593131,
  title = {Characterization of a novel function-blocking antibody targeted against the platelet P2Y1 receptor.},
  author = {["Karim Z", "Vemana H", "Alshbool F", "Lin O", "Alshehri A", "Javaherizadeh P", "Paez Espinosa E", "Khasawneh F"]},
  journal = {Arteriosclerosis, thrombosis, and vascular biology},
  year = {2015},
  pmid = {25593131},
  doi = {10.1161/ATVBAHA.114.304509},
}

@article{pmid25719930,
  title = {Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans.},
  author = {Todd JN, Poon W, Lyssenko V, Groop L, Nichols B, Wilmot M, Robson S, Enjyoji K, Herman MA, Hu C},
  journal = {J Clin Endocrinol Metab},
  year = {2015},
  pmid = {25719930},
  doi = {10.1210/jc.2014-4160},
  url = {https://pubmed.ncbi.nlm.nih.gov/25719930},
}

@article{pmid24143878,
  title = {Dysregulation of leukocyte gene expression in women with medication-refractory depression versus healthy non-depressed controls.},
  author = {Iacob E, Light KC, Tadler SC, Weeks HR, White AT, Hughen RW, Vanhaitsma TA, Bushnell L, Light AR},
  journal = {BMC psychiatry},
  year = {2013},
  pmid = {24143878},
  doi = {10.1186/1471-244X-13-273},
  url = {https://pubmed.ncbi.nlm.nih.gov/24143878/},
}

@article{pmid28615609,
  title = {Evidence of HPV subtypes linked with cervical cancer in Nepal.},
  author = {["Bhusal C", "Manandhar S", "Singh M", "Shah A", "Neupane S", "Karmacharya D", "Cuschieri K", "Cubie H", "Gilbert D", "Dixit S"]},
  journal = {WHO South-East Asia journal of public health},
  year = {2012},
  pmid = {28615609},
  doi = {10.4103/2224-3151.207046},
}

@article{pmid12787128,
  title = {Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes.},
  author = {Greig AV, Linge C, Terenghi G, McGrouther DA, Burnstock G},
  journal = {The Journal of investigative dermatology},
  year = {2003},
  pmid = {12787128},
  doi = {10.1046/j.1523-1747.2003.12261.x},
  url = {https://pubmed.ncbi.nlm.nih.gov/12787128/},
}