% Bibliography for hypothesis h-019ad538
% Title: Temporal Decoupling via Circadian Clock Reset
% Generated: 2026-04-28T14:07:09Z

@article{pmid41092646,
  title = {Multifunctional hydrogel delivery of mesenchymal stem cell secretome suppresses neutrophil extracellular trap formation and promotes diabetic wound healing via PGE2/BMAL1 pathway.},
  author = {Lin L, Liang X, Xu Z, Li Y, Guo Z et al.},
  journal = {Biomaterials},
  year = {2026},
  pmid = {41092646},
  doi = {doi: 10.1016/j.biomaterials.2025.123764},
  url = {https://pubmed.ncbi.nlm.nih.gov/41092646/},
}
  % freshness_score = 1.0000

@article{pmid41355044,
  title = {Pharmacological modulation of circadian rhythms in brain microvasculature.},
  author = {Yang Z, Kim M, Montgomery M, Lewandowski A, Ho A et al.},
  journal = {J Cereb Blood Flow Metab},
  year = {2026},
  pmid = {41355044},
  doi = {doi: 10.1177/0271678X251399116},
  url = {https://pubmed.ncbi.nlm.nih.gov/41355044/},
}
  % freshness_score = 1.0000

@article{pmid41486525,
  title = {The Liver Clock Tunes Transcriptional Rhythms in Skeletal Muscle to Regulate Mitochondrial Function.},
  author = {Sica V, Sato T, Tsialtas I, Hernandez S, Chen S et al.},
  journal = {J Biol Rhythms},
  year = {2026},
  pmid = {41486525},
  doi = {doi: 10.1177/07487304251386926},
  url = {https://pubmed.ncbi.nlm.nih.gov/41486525/},
}
  % freshness_score = 1.0000

@article{pmid41520235,
  title = {When Clocks Go Rogue: Circadian Rhythms and the Rise of Cancer.},
  author = {Robinson AS, Bennett S, Sato S},
  journal = {J Biol Rhythms},
  year = {2026},
  pmid = {41520235},
  doi = {doi: 10.1177/07487304251391270},
  url = {https://pubmed.ncbi.nlm.nih.gov/41520235/},
}
  % freshness_score = 1.0000

@article{pmid41578008,
  title = {Glycaemic, appetite and circadian benefits of a dairy-enriched diet with high-protein breakfast and early daytime-restricted carbohydrate intake in type 2 diabetes: a randomised crossover trial.},
  author = {Tsameret S, Froy O, Matz Y, Landau Z, Twito O et al.},
  journal = {Diabetologia},
  year = {2026},
  pmid = {41578008},
  doi = {doi: 10.1007/s00125-025-06658-2},
  url = {https://pubmed.ncbi.nlm.nih.gov/41578008/},
}
  % freshness_score = 1.0000

@article{pmid41763011,
  title = {Lifestyle factors and DNA methylation-based aging clocks: cross-sectional and longitudinal associations in the Singapore diet and healthy aging cohort.},
  author = {Shan J, Tay JH, Ye KX, Guo J, Cao L et al.},
  journal = {J Prev Alzheimers Dis},
  year = {2026},
  pmid = {41763011},
  doi = {doi: 10.1016/j.tjpad.2026.100522},
  url = {https://pubmed.ncbi.nlm.nih.gov/41763011/},
}
  % freshness_score = 1.0000

@article{pmid41809128,
  title = {Emerging role of epigenetic mechanisms in glaucoma and their translational potential.},
  author = {Kondkar AA, Sultan T, Azad TA, Al-Obeidan SA},
  journal = {Frontiers in genetics},
  year = {2026},
  pmid = {41809128},
  doi = {10.3389/fgene.2026.1781271},
  url = {https://pubmed.ncbi.nlm.nih.gov/41809128/},
}
  % freshness_score = 1.0000

@article{pmid41845938,
  title = {Unveiling the 12-Hour Ultradian Rhythm: Biological Foundations, Mechanistic Insights, and Potential Applications.},
  author = {Song J, Wang C, Li H, Wang T, Jiao X},
  journal = {Cell biochemistry and function},
  year = {2026},
  pmid = {41845938},
  doi = {10.1002/cbf.70195},
  url = {https://pubmed.ncbi.nlm.nih.gov/41845938/},
}
  % freshness_score = 1.0000

@article{pmid41886887,
  title = {Epigenetics and the gut-brain axis: Insights into DNA methylation, aging, and Alzheimer disease.},
  author = {Kumar V, Shukla R, Gangani S, Joseph R, Jain S, Yadav H},
  journal = {The Journal of pharmacology and experimental therapeutics},
  year = {2026},
  pmid = {41886887},
  doi = {10.1016/j.jpet.2026.104299},
  url = {https://pubmed.ncbi.nlm.nih.gov/41886887/},
}
  % freshness_score = 1.0000

@article{pmid41922126,
  title = {The neuroprotective role of eugenol against glyphosate-induced toxicity in rats: Modulation of oxidative stress, inflammation, ER stress and apoptotic signaling pathways.},
  author = {Bolat İ, Alat Ö, Orhan B, Dereli E, Tekin S, Laçin BB, Bolat M, Kapakin KAT, Sağlam YS},
  journal = {Tissue & cell},
  year = {2026},
  pmid = {41922126},
  doi = {10.1016/j.tice.2026.103509},
  url = {https://pubmed.ncbi.nlm.nih.gov/41922126/},
}
  % freshness_score = 1.0000

@article{pmid41922265,
  title = {Roles of Temperature and Reactive Oxygen Species in Circadian Rhythms and Thermosensitivity.},
  author = {Miyake T},
  journal = {Biological & pharmaceutical bulletin},
  year = {2026},
  pmid = {41922265},
  doi = {10.1248/bpb.b25-00811},
  url = {https://pubmed.ncbi.nlm.nih.gov/41922265/},
}
  % freshness_score = 1.0000

@article{pmid41922784,
  title = {Author Correction: CLOCK and BMAL1 stabilize and activate RHOA to promote F-actin formation in cancer cells.},
  author = {Ma Teng-Jiao; Zhang Zhi-Wei; Lu Yi-Lu; Zhang Ying-Ying; Tao Da-Chang; Liu Yun-Qiang; Ma Yong-Xin},
  journal = {Experimental & molecular medicine},
  year = {2026},
  pmid = {41922784},
  doi = {10.1038/s12276-026-01722-2},
  url = {https://pubmed.ncbi.nlm.nih.gov/41922784/},
}
  % freshness_score = 1.0000

@article{pmid41923233,
  title = {Effects of circadian rhythms on antimicrobial peptide concentrations in lactating goat milk.},
  author = {Liang ZL, Nii T, Sugino T, Isobe N},
  journal = {BMC veterinary research},
  year = {2026},
  pmid = {41923233},
  doi = {10.1186/s12917-026-05444-5},
  url = {https://pubmed.ncbi.nlm.nih.gov/41923233/},
}
  % freshness_score = 1.0000

@article{pmid41926119,
  title = {Prolonged Dual Hypothermic Oxygenated Machine Perfusion for Daytime Liver Transplant.},
  author = {Bodewes SB, Woltjes LC, Thorne AM, Eden J, Lantinga VA, Lascaris B, Blokzijl H, Fouraschen SMG, Hartog H, Vos JJ, Lisman T, de Meijer VE, DHOPE-PRO Investigators},
  journal = {JAMA network open},
  year = {2026},
  pmid = {41926119},
  doi = {10.1001/jamanetworkopen.2026.5039},
  url = {https://pubmed.ncbi.nlm.nih.gov/41926119/},
}
  % freshness_score = 1.0000

@article{pmid40250404,
  title = {From geroscience to precision geromedicine: Understanding and managing aging.},
  author = {Kroemer G, Maier AB, Cuervo AM, Gladyshev VN, Ferrucci L, Gorbunova V, Kennedy BK, Rando TA, Seluanov A, Sierra F},
  journal = {Cell},
  year = {2025},
  pmid = {40250404},
  doi = {10.1016/j.cell.2025.03.011},
  url = {https://pubmed.ncbi.nlm.nih.gov/40250404},
}
  % freshness_score = 0.8706

@article{pmid40588189,
  title = {Circadian Rhythms in Gastroenterology: The Biological Clock's Impact on Gut Health.},
  author = {Bishehsari F, Post Z, Swanson GR, Keshavarzian A},
  journal = {Gastroenterology},
  year = {2025},
  pmid = {40588189},
  doi = {10.1053/j.gastro.2025.06.017},
  url = {https://pubmed.ncbi.nlm.nih.gov/40588189},
}
  % freshness_score = 0.8706

@article{pmid39007272,
  title = {Circadian disruption, clock genes, and metabolic health.},
  author = {Schrader LA, Ronnekleiv-Kelly SM, Hogenesch JB, Bradfield CA, Malecki KM},
  journal = {J Clin Invest},
  year = {2024},
  pmid = {39007272},
  doi = {10.1172/JCI170998},
  url = {https://pubmed.ncbi.nlm.nih.gov/39007272},
}
  % freshness_score = 0.7579

@article{pmid39139571,
  title = {Circadian rhythms and breast cancer: unraveling the biological clock's role in tumor microenvironment and ageing.},
  author = {Yan Y, Su L, Huang S, He Q, Lu J, Luo H, Xu K, Yang G, Huang S, Chi H},
  journal = {Frontiers in immunology},
  year = {2024},
  pmid = {39139571},
  doi = {10.3389/fimmu.2024.1444426},
  url = {https://pubmed.ncbi.nlm.nih.gov/39139571/},
}
  % freshness_score = 0.7579

@article{pmid36675058,
  title = {The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship.},
  author = {Ono M, Ando H, Daikoku T, Fujiwara T, Mieda M, Mizumoto Y, Iizuka T, Kagami K, Hosono T, Nomura S, Toyoda N, Sekizuka-Kagami N, Maida Y, Kuji N, Nishi H, Fujiwara H},
  journal = {International journal of molecular sciences},
  year = {2023},
  pmid = {36675058},
  doi = {10.3390/ijms24021545},
  url = {https://pubmed.ncbi.nlm.nih.gov/36675058/},
}
  % freshness_score = 0.6598

@article{pmid37657418,
  title = {Biomarkers of aging for the identification and evaluation of longevity interventions.},
  author = {Moqri M, Herzog C, Poganik JR, Biomarkers of Aging Consortium, Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA},
  journal = {Cell},
  year = {2023},
  pmid = {37657418},
  doi = {10.1016/j.cell.2023.08.003},
  url = {https://pubmed.ncbi.nlm.nih.gov/37657418},
}
  % freshness_score = 0.6598

@article{pmid34759373,
  title = {Circadian rhythms in neurodegenerative disorders.},
  author = {Nassan M, Videnovic A},
  journal = {Nature reviews. Neurology},
  year = {2022},
  pmid = {34759373},
  doi = {10.1038/s41582-021-00577-7},
  url = {https://pubmed.ncbi.nlm.nih.gov/34759373/},
}
  % freshness_score = 0.5743

@article{pmid34998857,
  title = {Circadian disruption and cisplatin chronotherapy for mammary carcinoma.},
  author = {["Koritala B", "Porter K", "Sarkar S", "Gaddameedhi S"]},
  journal = {Toxicology and applied pharmacology},
  year = {2022},
  pmid = {34998857},
  doi = {10.1016/j.taap.2022.115863},
}
  % freshness_score = 0.5743

@article{pmid33384351,
  title = {Clocks, cancer, and chronochemotherapy.},
  author = {Sancar A, Van Gelder RN},
  journal = {Science},
  year = {2021},
  pmid = {33384351},
  doi = {10.1126/science.abb0738},
  url = {https://pubmed.ncbi.nlm.nih.gov/33384351},
}
  % freshness_score = 0.5000

@article{pmid27885006,
  title = {Mechanisms linking circadian clocks, sleep, and neurodegeneration.},
  author = {Musiek ES, Holtzman DM},
  journal = {Science},
  year = {2016},
  pmid = {27885006},
  doi = {10.1126/science.aah4968},
  url = {https://pubmed.ncbi.nlm.nih.gov/27885006/},
}
  % freshness_score = 0.2500